Atomistry » Arsenic » PDB 1b92-1fyx » 1b9f
Atomistry »
  Arsenic »
    PDB 1b92-1fyx »
      1b9f »

Arsenic in PDB 1b9f: Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity

Enzymatic activity of Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity

All present enzymatic activity of Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity:
2.7.7.49;

Protein crystallography data

The structure of Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity, PDB code: 1b9f was solved by J.Greenwald, V.Le, S.L.Butler, F.D.Bushman, S.Choe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.70
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 72.440, 72.440, 65.420, 90.00, 90.00, 120.00
R / Rfree (%) 24.3 / 28

Arsenic Binding Sites:

The binding sites of Arsenic atom in the Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity (pdb code 1b9f). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity, PDB code: 1b9f:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in 1b9f

Go back to Arsenic Binding Sites List in 1b9f
Arsenic binding site 1 out of 2 in the Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As300

b:33.6
occ:1.00
AS A:CAC300 0.0 33.6 1.0
O1 A:CAC300 1.3 43.0 1.0
C1 A:CAC300 2.2 36.2 1.0
SG A:CYS65 2.3 27.1 1.0
C2 A:CAC300 2.3 35.3 1.0
CB A:CYS65 3.2 26.7 1.0
OD1 A:ASN120 3.4 32.4 1.0
N A:CYS65 3.5 24.8 1.0
ND2 A:ASN120 3.5 29.4 1.0
CG A:ASN120 3.6 31.7 1.0
O A:HOH406 3.8 28.1 1.0
CA A:CYS65 3.8 24.7 1.0
O A:HOH433 4.0 44.9 1.0
C A:ASP64 4.0 26.7 1.0
OE2 A:GLU92 4.2 40.9 1.0
CG A:GLU92 4.3 41.1 1.0
OG1 A:THR97 4.5 25.9 1.0
CA A:ASP64 4.6 26.9 1.0
CB A:ASN120 4.7 31.8 1.0
O A:ASP64 4.7 25.8 1.0
CD A:GLU92 4.8 42.5 1.0
O A:HOH416 4.8 35.9 1.0

Arsenic binding site 2 out of 2 in 1b9f

Go back to Arsenic Binding Sites List in 1b9f
Arsenic binding site 2 out of 2 in the Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As400

b:37.4
occ:1.00
AS A:CAC400 0.0 37.4 1.0
O1 A:CAC400 1.3 38.6 1.0
C1 A:CAC400 2.2 36.9 1.0
C2 A:CAC400 2.3 36.7 1.0
SG A:CYS130 2.3 23.4 1.0
CB A:CYS130 3.0 24.9 1.0
CG2 A:ILE135 4.1 24.2 1.0
O A:ILE135 4.2 23.9 1.0
N A:GLN137 4.2 33.0 1.0
CB A:GLN137 4.3 38.4 1.0
C A:LYS136 4.3 30.8 1.0
CA A:CYS130 4.4 22.3 1.0
CA A:GLN137 4.5 35.7 1.0
O A:LYS136 4.5 29.5 1.0
C A:ILE135 4.6 23.9 1.0
CB A:ILE135 4.7 25.7 1.0
O A:HOH465 4.7 47.1 1.0
CA A:LYS136 4.7 31.4 1.0
N A:LYS136 4.8 26.4 1.0
O A:HOH452 4.9 40.1 1.0

Reference:

J.Greenwald, V.Le, S.L.Butler, F.D.Bushman, S.Choe. The Mobility of An Hiv-1 Integrase Active Site Loop Is Correlated with Catalytic Activity. Biochemistry V. 38 8892 1999.
ISSN: ISSN 0006-2960
PubMed: 10413462
DOI: 10.1021/BI9907173
Page generated: Sun Jul 6 22:49:56 2025

Last articles

Ca in 2VC2
Ca in 2VCP
Ca in 2VBO
Ca in 2VCC
Ca in 2VCA
Ca in 2VCB
Ca in 2VC9
Ca in 2VBN
Ca in 2VAY
Ca in 2VB6
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy