Arsenic in PDB 1qg3: Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4

The structure of Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4, PDB code: 1qg3 was solved by J.M.De Pereda, G.Wiche, R.C.Liddington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.15
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	59.040, 59.040, 246.050, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 26.2

The binding sites of Arsenic atom in the Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4 (pdb code 1qg3). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4, PDB code: 1qg3:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4 within 5.0Å range: probe atom residue distance (Å) B Occ A:As383 b:64.8 occ:0.50 AS A:CAC383 0.0 64.8 0.5 O2 A:CAC383 1.8 68.5 0.5 O1 A:CAC383 1.8 68.5 0.5 C2 A:CAC383 2.0 68.4 0.5 C1 A:CAC383 2.0 68.3 0.5 O A:HOH19 3.8 34.0 1.0 NH2 A:ARG1289 3.8 20.3 1.0 NE A:ARG1289 3.8 20.7 1.0 NZ A:LYS1271 4.0 34.5 1.0 CZ A:ARG1289 4.3 21.9 1.0 O A:HOH172 4.8 34.5 1.0 CE A:LYS1271 4.8 33.8 1.0 CG A:ARG1289 4.9 21.8 1.0 O A:HOH335 4.9 57.5 1.0 CD A:ARG1289 5.0 19.8 1.0

Arsenic binding site 2 out of 2 in the Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6 BETA4 within 5.0Å range: probe atom residue distance (Å) B Occ B:As382 b:62.8 occ:0.50 AS B:CAC382 0.0 62.8 0.5 O2 B:CAC382 1.8 66.3 0.5 O1 B:CAC382 1.8 66.3 0.5 C2 B:CAC382 2.0 64.3 0.5 C1 B:CAC382 2.0 64.3 0.5 NE B:ARG1289 3.7 17.8 1.0 NH2 B:ARG1289 3.8 14.6 1.0 O B:HOH20 3.9 33.0 1.0 CZ B:ARG1289 4.2 18.5 1.0 CG B:ARG1289 4.7 18.9 1.0 CD B:ARG1289 4.8 18.4 1.0 O B:ASN1287 5.0 20.6 1.0

J.M.De Pereda, G.Wiche, R.C.Liddington. Crystal Structure of A Tandem Pair of Fibronectin Type III Domains From the Cytoplasmic Tail of Integrin ALPHA6BETA4. Embo J. V. 18 4087 1999.
ISSN: ISSN 0261-4189
PubMed: 10428948
DOI: 10.1093/EMBOJ/18.15.4087