Arsenic in PDB 1tnd: The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S

The structure of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S, PDB code: 1tnd was solved by J.P.Noel, H.E.Hamm, P.B.Sigler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 2.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	74.500, 108.300, 79.000, 90.00, 112.30, 90.00
R / Rfree (%)	19 / n/a

The structure of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Arsenic atom in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S (pdb code 1tnd). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 6 binding sites of Arsenic where determined in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S, PDB code: 1tnd:
Jump to Arsenic binding site number: 1; 2; 3; 4; 5; 6;

Arsenic binding site 1 out of 6 in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S within 5.0Å range: probe atom residue distance (Å) B Occ A:As353 b:32.7 occ:1.00 SG A:CYS62 2.5 31.3 1.0 CB A:CYS62 3.4 22.2 1.0 O A:PRO165 3.7 12.1 1.0 O A:HOH424 3.9 16.6 1.0 CD1 B:ILE180 4.1 18.3 1.0 CG2 A:VAL164 4.4 20.9 1.0 O A:HOH549 4.5 33.8 1.0 O A:HOH370 4.5 36.4 1.0 CA A:LEU59 4.6 23.8 1.0 O A:HOH483 4.7 34.6 1.0 O A:SER58 4.7 29.5 1.0 CA A:CYS62 4.8 21.6 1.0 C A:PRO165 4.9 10.9 1.0 CD2 A:LEU59 4.9 7.9 1.0 O A:TYR57 5.0 18.4 1.0

Arsenic binding site 2 out of 6 in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S within 5.0Å range: probe atom residue distance (Å) B Occ A:As354 b:31.3 occ:1.00 SG A:CYS210 2.7 25.1 1.0 CB A:CYS210 3.3 19.6 1.0 CB A:VAL197 3.8 12.6 1.0 CG1 A:VAL197 4.0 8.8 1.0 CG2 A:VAL197 4.0 12.7 1.0 O A:HOH356 4.0 26.5 1.0 CD1 A:ILE180 4.1 7.1 1.0 CG1 A:ILE180 4.3 11.2 1.0 CA A:TRP207 4.4 23.2 1.0 O A:TRP207 4.5 29.4 1.0 CD1 A:TRP207 4.5 17.7 1.0 CG2 A:ILE180 4.6 10.1 1.0 CA A:CYS210 4.8 21.0 1.0 CG A:TRP207 4.9 20.7 1.0 C A:TRP207 5.0 26.1 1.0 O A:LYS206 5.0 24.4 1.0

Arsenic binding site 3 out of 6 in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S within 5.0Å range: probe atom residue distance (Å) B Occ B:As353 b:42.5 occ:1.00 SG B:CYS62 2.5 22.7 1.0 CB B:CYS62 3.4 13.4 1.0 O B:PRO165 3.6 21.6 1.0 O B:HOH417 4.0 17.5 1.0 O B:HOH387 4.2 37.5 1.0 CG1 B:VAL164 4.4 18.1 1.0 CA B:LEU59 4.6 21.0 1.0 O B:SER58 4.7 19.9 1.0 C B:PRO165 4.8 20.5 1.0 CA B:CYS62 4.8 16.8 1.0 O B:HOH418 4.9 28.9 1.0

Arsenic binding site 4 out of 6 in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 4 of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S within 5.0Å range: probe atom residue distance (Å) B Occ B:As354 b:33.8 occ:1.00 SG B:CYS210 2.6 29.7 1.0 O B:HOH432 2.8 42.0 1.0 CB B:CYS210 3.4 21.9 1.0 CB B:VAL197 3.8 20.6 1.0 CG2 B:VAL197 3.9 20.8 1.0 CG1 B:VAL197 4.1 15.4 1.0 O B:HOH366 4.1 18.0 1.0 CD1 B:ILE180 4.2 18.3 1.0 CG1 B:ILE180 4.2 25.8 1.0 O B:TRP207 4.5 24.1 1.0 CD1 B:TRP207 4.5 31.9 1.0 NZ B:LYS206 4.5 38.5 1.0 CA B:TRP207 4.6 25.0 1.0 CG2 B:ILE180 4.6 17.1 1.0 CA B:CYS210 4.8 24.1 1.0 CG B:TRP207 4.9 34.4 1.0

Arsenic binding site 5 out of 6 in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 5 of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S within 5.0Å range: probe atom residue distance (Å) B Occ C:As353 b:38.5 occ:1.00 SG C:CYS62 2.6 33.0 1.0 CB C:CYS62 3.2 24.4 1.0 O C:PRO165 3.5 23.1 1.0 CD1 A:ILE180 4.0 7.1 1.0 O C:HOH358 4.3 24.5 1.0 CG1 C:VAL164 4.4 11.4 1.0 CA C:LEU59 4.5 15.8 1.0 O C:SER58 4.5 24.3 1.0 CA C:CYS62 4.7 23.1 1.0 C C:PRO165 4.7 20.7 1.0 O C:HOH393 4.9 23.8 1.0 O C:LEU59 4.9 19.1 1.0 CD1 C:LEU59 4.9 9.8 1.0 O C:HOH392 5.0 38.5 1.0 N C:LEU59 5.0 18.3 1.0

Arsenic binding site 6 out of 6 in the The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 6 of The 2.2 Angstroms Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S within 5.0Å range: probe atom residue distance (Å) B Occ C:As354 b:32.1 occ:1.00 SG C:CYS210 2.6 30.8 1.0 CB C:CYS210 3.2 23.6 1.0 CB C:VAL197 3.8 15.9 1.0 CG2 C:VAL197 4.0 16.3 1.0 CG1 C:VAL197 4.1 14.2 1.0 CG1 C:ILE180 4.3 14.3 1.0 CD1 C:TRP207 4.3 16.0 1.0 CD1 C:ILE180 4.3 12.6 1.0 CG2 C:ILE180 4.4 15.2 1.0 O C:HOH376 4.4 18.1 1.0 CA C:TRP207 4.4 24.2 1.0 O C:TRP207 4.6 23.3 1.0 CA C:CYS210 4.7 26.1 1.0 NZ C:LYS206 4.7 45.1 1.0 CG C:TRP207 4.9 21.5 1.0 NE1 C:TRP207 4.9 21.5 1.0 CB C:ILE180 5.0 17.6 1.0

J.P.Noel, H.E.Hamm, P.B.Sigler. The 2.2 A Crystal Structure of Transducin-Alpha Complexed with Gtp Gamma S. Nature V. 366 654 1993.
ISSN: ISSN 0028-0836
PubMed: 8259210
DOI: 10.1038/366654A0