Atomistry » Arsenic » PDB 1q2o-1yhc » 1w2k
Atomistry »
  Arsenic »
    PDB 1q2o-1yhc »
      1w2k »

Arsenic in PDB 1w2k: TF7A_4380 Complex

Enzymatic activity of TF7A_4380 Complex

All present enzymatic activity of TF7A_4380 Complex:
3.4.21.21;

Protein crystallography data

The structure of TF7A_4380 Complex, PDB code: 1w2k was solved by D.W.Banner, A.D'arcy, K.Groebke-Zbinden, J.Ackermann, D.Kirchhofer, Y.-H.Ji, T.B.Tschopp, S.Wallbaum, L.Weber, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.82 / 3.0
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 71.874, 82.638, 123.722, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1w2k:

The structure of TF7A_4380 Complex also contains other interesting chemical elements:

Calcium (Ca) 9 atoms

Arsenic Binding Sites:

The binding sites of Arsenic atom in the TF7A_4380 Complex (pdb code 1w2k). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the TF7A_4380 Complex, PDB code: 1w2k:

Arsenic binding site 1 out of 1 in 1w2k

Go back to Arsenic Binding Sites List in 1w2k
Arsenic binding site 1 out of 1 in the TF7A_4380 Complex


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of TF7A_4380 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
H:As1260

b:45.4
occ:0.50
AS H:CAC1260 0.0 45.4 0.5
O2 H:CAC1260 1.6 45.9 0.5
O1 H:CAC1260 1.6 44.6 0.5
C2 H:CAC1260 1.9 46.5 0.5
C1 H:CAC1260 1.9 46.4 0.5
ND1 H:HIS224 3.8 18.5 1.0
OG H:SER170B 3.8 22.6 1.0
N H:PHE225 4.1 5.2 1.0
O H:HOH2152 4.1 15.0 1.0
O H:PHE225 4.1 2.2 1.0
CB H:SER170B 4.3 24.2 1.0
CB H:HIS224 4.4 10.5 1.0
CA H:HIS224 4.4 7.8 1.0
CG H:HIS224 4.5 16.1 1.0
C H:HIS224 4.8 7.3 1.0
CE1 H:HIS224 4.8 18.2 1.0
CG2 H:VAL227 4.8 3.8 1.0
SG H:CYS168 4.8 5.1 1.0
CD1 H:ILE176 4.8 11.7 1.0
C H:PHE225 4.9 2.2 1.0
CA H:PHE225 4.9 2.7 1.0

Reference:

K.Groebke-Zbinden, D.W.Banner, J.Ackermann, A.D'arcy, D.Kirchhofer, Y.-H.Ji, T.B.Tschopp, S.Wallbaum, L.Weber. Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors Bioorg.Med.Chem.Lett. V. 15 817 2005.
ISSN: ISSN 0960-894X
PubMed: 15664864
DOI: 10.1016/J.BMCL.2004.10.092
Page generated: Tue Oct 27 16:47:35 2020

Last articles

Xe in 6AYK
Xe in 6QII
Xe in 6ASM
Xe in 5NSW
Xe in 6FY9
Xe in 5O1K
Xe in 5O27
Xe in 5M69
Xe in 5KPU
Xe in 5I63
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy