Atomistry » Arsenic » PDB 1q2o-1yhc » 1wn5
Atomistry »
  Arsenic »
    PDB 1q2o-1yhc »
      1wn5 »

Arsenic in PDB 1wn5: Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid

Enzymatic activity of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid

All present enzymatic activity of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid:
3.5.4.23;

Protein crystallography data

The structure of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid, PDB code: 1wn5 was solved by T.Kumasaka, M.Yamamoto, M.Furuichi, M.Nakasako, M.Kimura, I.Yamaguchi, T.Ueki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.61 / 1.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 54.672, 69.293, 144.714, 90.00, 90.00, 90.00
R / Rfree (%) 18.9 / 22

Other elements in 1wn5:

The structure of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid also contains other interesting chemical elements:

Zinc (Zn) 4 atoms

Arsenic Binding Sites:

The binding sites of Arsenic atom in the Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid (pdb code 1wn5). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 4 binding sites of Arsenic where determined in the Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid, PDB code: 1wn5:
Jump to Arsenic binding site number: 1; 2; 3; 4;

Arsenic binding site 1 out of 4 in 1wn5

Go back to Arsenic Binding Sites List in 1wn5
Arsenic binding site 1 out of 4 in the Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As2001

b:29.4
occ:0.72
AS A:CAC2001 0.0 29.4 0.7
O2 A:CAC2001 1.8 19.6 0.7
O1 A:CAC2001 1.8 24.5 0.7
C2 A:CAC2001 2.0 23.9 0.7
C1 A:CAC2001 2.0 26.0 0.7
ZN A:ZN1001 3.4 19.9 1.0
OE1 A:GLU56 3.5 19.2 1.0
OE2 A:GLU56 3.7 17.1 1.0
O A:HOH2043 3.8 17.1 1.0
N A:CYS88 4.0 16.2 1.0
CD A:GLU56 4.1 17.0 1.0
SG A:CYS54 4.1 19.1 1.0
CB A:CYS54 4.2 15.9 1.0
O A:SER86 4.5 17.9 1.0
CB A:CYS88 4.5 13.8 1.0
O A:HOH2023 4.5 19.6 1.0
CA A:PRO87 4.5 16.8 1.0
C A:PRO87 4.7 16.9 1.0
CD1 B:TYR126 4.8 29.5 1.0
CE1 B:TYR126 4.8 30.2 1.0
CA A:CYS88 4.9 16.0 1.0
SG A:CYS91 4.9 19.9 1.0
SG A:CYS88 4.9 17.5 1.0
CB A:ALA76 4.9 13.8 1.0
CG B:TYR126 5.0 29.5 1.0
CG1 A:VAL29 5.0 14.1 1.0
CZ B:TYR126 5.0 30.2 1.0

Arsenic binding site 2 out of 4 in 1wn5

Go back to Arsenic Binding Sites List in 1wn5
Arsenic binding site 2 out of 4 in the Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
B:As2002

b:31.4
occ:0.71
AS B:CAC2002 0.0 31.4 0.7
O2 B:CAC2002 1.8 25.1 0.7
O1 B:CAC2002 1.8 20.1 0.7
C2 B:CAC2002 2.0 26.7 0.7
C1 B:CAC2002 2.0 26.4 0.7
ZN B:ZN1002 3.4 21.2 1.0
OE1 B:GLU56 3.6 16.6 1.0
OE2 B:GLU56 3.6 18.9 1.0
O B:HOH2018 3.7 21.3 1.0
CD B:GLU56 4.0 16.8 1.0
N B:CYS88 4.0 15.9 1.0
SG B:CYS54 4.1 18.9 1.0
CB B:CYS54 4.2 15.8 1.0
O B:SER86 4.5 18.0 1.0
CB B:CYS88 4.5 17.6 1.0
CA B:PRO87 4.5 16.6 1.0
O B:HOH2017 4.6 23.3 1.0
C B:PRO87 4.7 16.7 1.0
CD1 A:TYR126 4.8 36.6 1.0
CE1 A:TYR126 4.8 36.2 1.0
CB B:ALA76 4.9 14.6 1.0
SG B:CYS91 4.9 18.8 1.0
CA B:CYS88 4.9 16.8 1.0
SG B:CYS88 4.9 18.1 1.0
CG1 B:VAL29 5.0 15.0 1.0
CG A:TYR126 5.0 37.0 1.0

Arsenic binding site 3 out of 4 in 1wn5

Go back to Arsenic Binding Sites List in 1wn5
Arsenic binding site 3 out of 4 in the Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
C:As2003

b:30.1
occ:0.58
AS C:CAC2003 0.0 30.1 0.6
O2 C:CAC2003 1.8 25.9 0.6
O1 C:CAC2003 1.8 19.9 0.6
C2 C:CAC2003 2.0 26.9 0.6
C1 C:CAC2003 2.0 24.9 0.6
ZN C:ZN1003 3.5 24.2 1.0
O C:HOH2016 3.6 19.6 1.0
OE1 C:GLU56 3.6 20.0 1.0
OE2 C:GLU56 3.6 22.8 1.0
N C:CYS88 4.0 21.2 1.0
CD C:GLU56 4.0 20.3 1.0
SG C:CYS54 4.1 19.6 1.0
CB C:CYS54 4.2 16.7 1.0
O C:SER86 4.4 23.1 1.0
CB C:CYS88 4.4 21.3 1.0
CA C:PRO87 4.5 20.5 1.0
O C:HOH2040 4.6 30.2 1.0
C C:PRO87 4.8 21.4 1.0
CA C:CYS88 4.8 20.9 1.0
SG C:CYS88 4.9 22.0 1.0
SG C:CYS91 4.9 22.4 1.0
CB C:ALA76 4.9 18.5 1.0

Arsenic binding site 4 out of 4 in 1wn5

Go back to Arsenic Binding Sites List in 1wn5
Arsenic binding site 4 out of 4 in the Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 4 of Crystal Structure of Blasticidin S Deaminase (Bsd) Complexed with Cacodylic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
D:As2004

b:32.5
occ:0.58
AS D:CAC2004 0.0 32.5 0.6
O2 D:CAC2004 1.8 25.7 0.6
O1 D:CAC2004 1.8 22.8 0.6
C2 D:CAC2004 2.0 28.1 0.6
C1 D:CAC2004 2.0 27.1 0.6
ZN D:ZN1004 3.4 25.3 1.0
OE2 D:GLU56 3.6 24.0 1.0
OE1 D:GLU56 3.7 22.1 1.0
O D:HOH2038 3.9 21.8 1.0
SG D:CYS54 4.0 22.3 1.0
N D:CYS88 4.0 22.1 1.0
CD D:GLU56 4.1 21.8 1.0
CB D:CYS54 4.2 18.3 1.0
O D:SER86 4.4 26.8 1.0
O D:HOH2045 4.4 28.5 1.0
CB D:CYS88 4.4 21.2 1.0
CA D:PRO87 4.5 23.5 1.0
C D:PRO87 4.7 24.2 1.0
SG D:CYS88 4.8 21.8 1.0
CA D:CYS88 4.9 21.6 1.0
CD1 C:TYR126 4.9 49.6 1.0
SG D:CYS91 4.9 23.0 1.0
CE1 C:TYR126 4.9 49.7 1.0
CB D:ALA76 5.0 22.1 1.0

Reference:

T.Kumasaka, M.Yamamoto, M.Furuichi, M.Nakasako, A.H.Teh, M.Kimura, I.Yamaguchi, T.Ueki. Crystal Structures of Blasticidin S Deaminase (Bsd): Implications For Dynamic Properties of Catalytic Zinc J.Biol.Chem. V. 282 37103 2007.
ISSN: ISSN 0021-9258
PubMed: 17959604
DOI: 10.1074/JBC.M704476200
Page generated: Wed Jul 10 11:16:10 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy