Arsenic in the structure of Potassium Channel Kcsa-Fab Complex in Thallium With Tetraethylarsonium (Teas) (pdb 2boc)

The binding sites of Arsenic atom in the structure of Potassium Channel Kcsa-Fab Complex in Thallium With Tetraethylarsonium (Teas) (pdb code 2boc). This binding sites where shown with 5.0 Angstroms radius around Arsenic atom. The 2boc structure was solved by M.J.LENAEUS, M.VAMVOUKA, P.J.FOCIA, A.GROSS, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 25.0-3.0 Space group I4 a (A) 154.680 b (A) 154.680 c (A) 76.190 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 22.2 Rfree (%) 25 Arsenic Binding Sites: Arsenic binding site 1 out of 2 in 2boc Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Arsenic in the PDB 2boc. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Arsenic atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Tyr78, L: T1a1, conact list: Atom Atom Distance (A) As O C:Tyr78 4.77 As C6 L:T1a1 2.81 As C6 L:T1a1 2.85 As C5 L:T1a1 1.90 As C5 L:T1a1 1.93 As C7 L:T1a1 1.90 As C7 L:T1a1 1.85 As C4 L:T1a1 2.81 As C4 L:T1a1 2.77 As C1 L:T1a1 1.89 As C1 L:T1a1 1.94 As C3 L:T1a1 1.90 As C3 L:T1a1 1.89 As AS L:T1a1 0.00 As AS L:T1a1 0.07 As C8 L:T1a1 2.81 As C8 L:T1a1 2.75 As C2 L:T1a1 2.80 As C2 L:T1a1 2.84 interactive model: Arsenic binding site 2 out of 2 in 2boc Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Arsenic in the PDB 2boc. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Arsenic atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Tyr78, C: Gly79, L: T1a1, conact list: Atom Atom Distance (A) As O C:Tyr78 4.72 As O C:Gly79 4.95 As C6 L:T1a1 2.84 As C6 L:T1a1 2.80 As C5 L:T1a1 1.94 As C5 L:T1a1 1.90 As C7 L:T1a1 1.89 As C7 L:T1a1 1.90 As C4 L:T1a1 2.87 As C4 L:T1a1 2.80 As C1 L:T1a1 1.84 As C1 L:T1a1 1.90 As C3 L:T1a1 1.93 As C3 L:T1a1 1.90 As AS L:T1a1 0.07 As AS L:T1a1 0.00 As C8 L:T1a1 2.78 As C8 L:T1a1 2.81 As C2 L:T1a1 2.74 As C2 L:T1a1 2.80 interactive model: