Arsenic in PDB 2g6o: Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co

All present enzymatic activity of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co:
1.14.13.39;

The structure of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co, PDB code: 2g6o was solved by H.Li, J.Igarashi, J.Jamal, W.Yang, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.96 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	57.698, 106.382, 155.897, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 24

The structure of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co also contains other interesting chemical elements:

Iron	(Fe)	2 atoms
Zinc	(Zn)	1 atom

The binding sites of Arsenic atom in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co (pdb code 2g6o). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co, PDB code: 2g6o:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co within 5.0Å range: probe atom residue distance (Å) B Occ A:As950 b:51.2 occ:1.00 AS A:CAC950 0.0 51.2 1.0 C1 A:CAC950 1.8 43.6 1.0 C2 A:CAC950 1.8 45.7 1.0 SG A:CYS384 2.3 39.9 1.0 CB A:CYS384 3.3 34.7 1.0 O A:HOH1204 3.5 52.9 1.0 CA A:CYS384 4.0 33.4 1.0 CD1 A:LEU328 4.5 32.9 1.0 CE3 A:TRP324 4.6 34.8 1.0 N A:CYS384 4.8 32.4 1.0 O A:HOH1200 4.9 45.9 1.0 CD2 A:TRP324 4.9 34.7 1.0

Arsenic binding site 2 out of 2 in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co within 5.0Å range: probe atom residue distance (Å) B Occ B:As950 b:48.1 occ:1.00 AS B:CAC950 0.0 48.1 1.0 C1 B:CAC950 1.8 46.8 1.0 C2 B:CAC950 1.8 46.8 1.0 SG B:CYS384 2.3 43.4 1.0 CB B:CYS384 3.0 40.7 1.0 CA B:CYS384 3.6 40.7 1.0 CE3 B:TRP324 4.3 44.2 1.0 CD2 B:TRP324 4.5 44.0 1.0 CB B:TRP324 4.5 42.3 1.0 N B:CYS384 4.6 40.2 1.0 CG B:TRP324 4.7 43.4 1.0 C B:CYS384 4.8 40.8 1.0 O B:CYS384 4.9 40.2 1.0 CZ3 B:TRP324 5.0 44.2 1.0

H.Li, J.Igarashi, J.Jamal, W.Yang, T.L.Poulos. Structural Studies of Constitutive Nitric Oxide Synthases with Diatomic Ligands Bound. J.Biol.Inorg.Chem. V. 11 753 2006.
ISSN: ISSN 0949-8257
PubMed: 16804678
DOI: 10.1007/S00775-006-0123-8