Atomistry » Arsenic » PDB 1z6b-2im2 » 2ilz
Atomistry »
  Arsenic »
    PDB 1z6b-2im2 »
      2ilz »

Arsenic in PDB 2ilz: Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+

Enzymatic activity of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+

All present enzymatic activity of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+:
2.7.7.48;

Protein crystallography data

The structure of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+, PDB code: 2ilz was solved by A.A.Thompson, O.B.Peersen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.30 / 2.50
Space group P 65
Cell size a, b, c (Å), α, β, γ (°) 128.159, 128.159, 112.610, 90.00, 90.00, 120.00
R / Rfree (%) 23 / 25.5

Other elements in 2ilz:

The structure of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+ also contains other interesting chemical elements:

Manganese (Mn) 2 atoms
Sodium (Na) 2 atoms

Arsenic Binding Sites:

The binding sites of Arsenic atom in the Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+ (pdb code 2ilz). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 4 binding sites of Arsenic where determined in the Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+, PDB code: 2ilz:
Jump to Arsenic binding site number: 1; 2; 3; 4;

Arsenic binding site 1 out of 4 in 2ilz

Go back to Arsenic Binding Sites List in 2ilz
Arsenic binding site 1 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As96

b:86.2
occ:1.00
 AS A:CAS96 0.0 86.2 1.0
CE2 A:CAS96 2.2 83.8 1.0
CE1 A:CAS96 2.3 84.5 1.0
SG A:CAS96 2.3 81.9 1.0
CB A:CAS96 3.1 77.3 1.0
OD2 A:ASP99 4.0 73.3 1.0
CG A:ASP99 4.4 72.0 1.0
CA A:CAS96 4.6 75.4 1.0
OD1 A:ASP99 4.6 73.0 1.0
CB A:GLU98 4.9 76.9 1.0
O A:CAS96 5.0 75.0 1.0

Arsenic binding site 2 out of 4 in 2ilz

Go back to Arsenic Binding Sites List in 2ilz
Arsenic binding site 2 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As212

b:52.0
occ:1.00
 AS A:CAS212 0.0 52.0 1.0
CE2 A:CAS212 2.2 47.9 1.0
CE1 A:CAS212 2.2 52.9 1.0
SG A:CAS212 2.3 43.5 1.0
CB A:CAS212 3.2 38.8 1.0
O A:ALA209 3.5 31.5 1.0
CD1 A:LEU374 3.6 43.6 1.0
O A:CAS212 3.6 35.4 1.0
CA A:CAS212 3.9 36.2 1.0
C A:CAS212 3.9 34.5 1.0
N A:CAS212 4.0 36.7 1.0
CE2 A:TYR326 4.2 43.4 1.0
CG A:PRO214 4.3 29.5 1.0
CD2 A:TYR326 4.3 40.1 1.0
CD A:PRO214 4.3 30.0 1.0
C A:ALA209 4.5 30.5 1.0
N A:ASP213 4.8 33.7 1.0
CB A:ALA209 4.8 28.9 1.0
CZ A:TYR326 4.9 42.9 1.0
N A:GLY211 4.9 34.6 1.0
C A:GLY211 4.9 35.8 1.0
CG A:LEU374 5.0 42.5 1.0
O A:HOH525 5.0 54.3 1.0

Arsenic binding site 3 out of 4 in 2ilz

Go back to Arsenic Binding Sites List in 2ilz
Arsenic binding site 3 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As281

b:47.6
occ:1.00
 AS A:CAS281 0.0 47.6 1.0
CE2 A:CAS281 2.2 45.0 1.0
CE1 A:CAS281 2.2 46.8 1.0
SG A:CAS281 2.2 41.1 1.0
CB A:CAS281 3.1 46.3 1.0
CA A:CAS281 3.8 48.2 1.0
O A:SER271 3.9 49.2 1.0
C A:SER271 4.1 50.8 1.0
CA A:HIS272 4.2 51.9 1.0
N A:HIS272 4.3 51.6 1.0
CZ2 A:TRP5 4.3 38.4 1.0
CB A:HIS272 4.3 51.8 1.0
C A:CAS281 4.7 48.3 1.0
CG A:HIS272 4.7 51.4 1.0
N A:VAL282 4.8 46.7 1.0
CD2 A:HIS272 4.8 51.8 1.0
CE2 A:TRP5 4.9 39.7 1.0
N A:CAS281 4.9 49.5 1.0
CA A:SER271 4.9 50.3 1.0
CH2 A:TRP5 5.0 39.5 1.0

Arsenic binding site 4 out of 4 in 2ilz

Go back to Arsenic Binding Sites List in 2ilz
Arsenic binding site 4 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 4 of Crystal Structure of Poliovirus Polymerase Complexed with Gtp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As290

b:75.6
occ:1.00
 AS A:CAS290 0.0 75.6 1.0
CE2 A:CAS290 2.2 73.3 1.0
CE1 A:CAS290 2.3 74.0 1.0
SG A:CAS290 2.3 70.6 1.0
CB A:CAS290 3.1 65.1 1.0
SD A:MET187 3.7 58.6 1.0
CD2 A:LEU268 3.8 37.5 1.0
CB A:SER179 4.1 49.8 1.0
CA A:CAS290 4.2 61.7 1.0
CG A:LEU268 4.4 40.3 1.0
CD2 A:LEU154 4.6 47.4 1.0
CE A:MET187 4.7 59.3 1.0
OG A:SER179 4.8 48.5 1.0
N A:SER291 4.8 59.1 1.0
CB A:ASP183 4.9 58.6 1.0
CD2 A:TYR267 4.9 67.2 1.0

Reference:

A.A.Thompson, R.A.Albertini, O.B.Peersen. Stabilization of Poliovirus Polymerase By Ntp Binding and Fingers-Thumb Interactions. J.Mol.Biol. V. 366 1459 2007.
ISSN: ISSN 0022-2836
PubMed: 17223130
DOI: 10.1016/J.JMB.2006.11.070
Page generated: Wed Jul 10 11:24:10 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy