Atomistry » Arsenic » PDB 1z6b-2im2 » 2im1
Atomistry »
  Arsenic »
    PDB 1z6b-2im2 »
      2im1 »

Arsenic in PDB 2im1: Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+

Enzymatic activity of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+

All present enzymatic activity of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+:
2.7.7.48;

Protein crystallography data

The structure of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+, PDB code: 2im1 was solved by A.A.Thompson, O.B.Peersen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.20 / 2.50
Space group P 65
Cell size a, b, c (Å), α, β, γ (°) 128.942, 128.942, 112.979, 90.00, 90.00, 120.00
R / Rfree (%) 23.9 / 26.8

Other elements in 2im1:

The structure of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+ also contains other interesting chemical elements:

Manganese (Mn) 3 atoms
Sodium (Na) 1 atom

Arsenic Binding Sites:

The binding sites of Arsenic atom in the Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+ (pdb code 2im1). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 4 binding sites of Arsenic where determined in the Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+, PDB code: 2im1:
Jump to Arsenic binding site number: 1; 2; 3; 4;

Arsenic binding site 1 out of 4 in 2im1

Go back to Arsenic Binding Sites List in 2im1
Arsenic binding site 1 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As96

b:86.1
occ:1.00
 AS A:CAS96 0.0 86.1 1.0
CE2 A:CAS96 2.2 84.1 1.0
CE1 A:CAS96 2.3 84.6 1.0
SG A:CAS96 2.3 82.5 1.0
CB A:CAS96 3.1 78.3 1.0
OD2 A:ASP99 4.0 72.5 1.0
CA A:CAS96 4.6 76.5 1.0
CG A:ASP99 4.6 72.5 1.0
CB A:GLU98 5.0 78.2 1.0

Arsenic binding site 2 out of 4 in 2im1

Go back to Arsenic Binding Sites List in 2im1
Arsenic binding site 2 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As212

b:48.0
occ:1.00
 AS A:CAS212 0.0 48.0 1.0
CE1 A:CAS212 2.2 48.5 1.0
CE2 A:CAS212 2.2 43.5 1.0
SG A:CAS212 2.3 34.5 1.0
CB A:CAS212 3.3 32.5 1.0
O A:ALA209 3.4 27.0 1.0
O A:CAS212 3.5 29.7 1.0
CD1 A:LEU374 3.7 38.9 1.0
C A:CAS212 3.9 27.3 1.0
CA A:CAS212 3.9 28.8 1.0
N A:CAS212 3.9 31.0 1.0
C A:ALA209 4.4 26.4 1.0
CG A:PRO214 4.4 25.5 1.0
CD A:PRO214 4.4 23.7 1.0
CE2 A:TYR326 4.6 39.4 1.0
CD2 A:TYR326 4.6 36.9 1.0
CB A:ALA209 4.7 22.8 1.0
N A:ASP213 4.8 24.8 1.0
N A:GLY211 4.9 33.2 1.0
O A:HOH519 5.0 35.8 1.0
C A:GLY211 5.0 32.1 1.0

Arsenic binding site 3 out of 4 in 2im1

Go back to Arsenic Binding Sites List in 2im1
Arsenic binding site 3 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As281

b:48.5
occ:1.00
 AS A:CAS281 0.0 48.5 1.0
CE2 A:CAS281 2.2 44.8 1.0
CE1 A:CAS281 2.2 45.9 1.0
SG A:CAS281 2.2 41.3 1.0
CB A:CAS281 3.1 43.6 1.0
O A:SER271 3.9 43.6 1.0
CA A:CAS281 3.9 45.0 1.0
C A:SER271 4.1 45.1 1.0
CA A:HIS272 4.1 45.7 1.0
CB A:HIS272 4.2 44.3 1.0
N A:HIS272 4.2 44.8 1.0
CZ2 A:TRP5 4.5 35.9 1.0
CG A:HIS272 4.5 43.2 1.0
CD2 A:HIS272 4.7 42.2 1.0
C A:CAS281 4.8 43.8 1.0
N A:VAL282 4.9 41.2 1.0
CA A:SER271 4.9 45.6 1.0
N A:CAS281 5.0 47.0 1.0

Arsenic binding site 4 out of 4 in 2im1

Go back to Arsenic Binding Sites List in 2im1
Arsenic binding site 4 out of 4 in the Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 4 of Crystal Structure of Poliovirus Polymerase Complexed with Ctp and MN2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As290

b:70.7
occ:1.00
 AS A:CAS290 0.0 70.7 1.0
CE2 A:CAS290 2.2 67.4 1.0
CE1 A:CAS290 2.3 69.2 1.0
SG A:CAS290 2.3 63.7 1.0
CB A:CAS290 3.1 55.8 1.0
SD A:MET187 3.7 51.2 1.0
CD2 A:LEU268 3.8 33.9 1.0
CB A:SER179 4.1 50.1 1.0
CA A:CAS290 4.2 52.8 1.0
CD2 A:LEU154 4.6 43.2 1.0
CG A:LEU268 4.6 37.7 1.0
OG A:SER179 4.7 48.8 1.0
CB A:ASP183 4.8 57.5 1.0
CD2 A:TYR267 4.9 62.2 1.0
N A:SER291 5.0 49.5 1.0
CE A:MET187 5.0 51.5 1.0

Reference:

A.A.Thompson, R.A.Albertini, O.B.Peersen. Stabilization of Poliovirus Polymerase By Ntp Binding and Fingers-Thumb Interactions. J.Mol.Biol. V. 366 1459 2007.
ISSN: ISSN 0022-2836
PubMed: 17223130
DOI: 10.1016/J.JMB.2006.11.070
Page generated: Sun Jul 6 23:11:02 2025

Last articles

Cl in 3ZZF
Cl in 3ZZW
Cl in 3ZXV
Cl in 3ZXR
Cl in 3ZZE
Cl in 3ZXQ
Cl in 3ZX6
Cl in 3ZXD
Cl in 3ZX2
Cl in 3ZX0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy