Chemical elements
  Arsenic
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    Detection of Arsenic
    Estimation of Arsenic
    Physiological Properties
    PDB 1b92-1ihu
    PDB 1ii0-1tnd
    PDB 1tql-2hmh
    PDB 2hx2-2xnq
      2hx2
      2hyp
      2hze
      2i0k
      2ia5
      2ily
      2ilz
      2im0
      2im1
      2im2
      2im3
      2iuc
      2iwr
      2iyo
      2j13
      2j4z
      2j6e
      2jbh
      2jfs
      2jgo
      2nse
      2o4m
      2o4q
      2o6w
      2oui
      2pnk
      2pq3
      2ra8
      2rl7
      2v5c
      2v96
      2v97
      2v98
      2vdk
      2vdl
      2veq
      2vqg
      2vqh
      2vqk
      2vql
      2vs0
      2vw8
      2w9j
      2wa7
      2wta
      2x2o
      2x2p
      2x2q
      2xfv
      2xnq
    PDB 2xod-3htw
    PDB 3hzf-3od5
    PDB 3ouu-9nse

Arsenic in the structure of Gtpase Like Domain of Centaurin Gamma 1 (Human) (pdb 2iwr)






The binding sites of Arsenic atom in the structure of Gtpase Like Domain of Centaurin Gamma 1 (Human) (pdb code 2iwr). This binding sites where shown with 5.0 Angstroms radius around Arsenic atom.
The 2iwr structure was solved by J.M.ELKINS, M.SOUNDARARAJAN, X.YANG, E.PAPAGRIGORIOU, M.SUNDSTROM, A.EDWARDS, C.ARROWSMITH, J.WEIGELT, D.A.DOYLE, STRUCTURAL GENOMICS CONSORTIUM (SGC), with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)45.7-1.5
Space groupP212121
a (A)36.256
b (A)62.146
c (A)67.498
alpha (°)90.00
beta (°)90.00
gamma (°)90.00
Rfactor (%)15
Rfree (%)21.4


Arsenic Binding Sites:

Arsenic binding site 1 out of 2 in 2iwr


Arsenic binding site 1 out of 2 in 2iwr
Click to enlarge
stereopicture of Arsenic binding site 1 out of 2 in 2iwr
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Arsenic in the PDB 2iwr. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Arsenic atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Arg197, A: Caf200, A: Ala201, A: Cys206, A: Ser207, A: Tyr208, A: Hoh2183, A: Hoh2184, A: Hoh2190,

conact list:


AtomAtomDistance (A)
AsO A:Arg1974.07
AsCB A:Arg1974.66
AsC A:Arg1974.86
AsCA A:Arg1974.70
AsO A:Caf2004.58
AsCB A:Caf2002.99
AsCE2 A:Caf2001.97
AsSG A:Caf2002.23
AsO1 A:Caf2001.93
AsAS A:Caf2000.00
AsC A:Caf2004.39
AsCE1 A:Caf2001.97
AsCA A:Caf2004.21
AsN A:Ala2014.13
AsCA A:Ala2014.80
AsO A:Cys2064.05
AsC A:Cys2064.83
AsC A:Ser2075.00
AsCA A:Ser2074.92
AsN A:Tyr2084.63
AsCB A:Tyr2084.52
AsO A:Hoh21834.92
AsO A:Hoh21844.91
AsO A:Hoh21904.94

interactive model:


Arsenic binding site 2 out of 2 in 2iwr


Arsenic binding site 2 out of 2 in 2iwr
Click to enlarge
stereopicture of Arsenic binding site 2 out of 2 in 2iwr
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Arsenic in the PDB 2iwr. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Arsenic atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Gln180, A: Asp181, A: Caf212, A: Thr214, A: Hoh2157, A: Hoh2161,

conact list:


AtomAtomDistance (A)
AsO A:Gln1803.92
AsOE1 A:Gln1804.42
AsCB A:Gln1803.95
AsC A:Gln1803.94
AsCA A:Gln1804.58
AsO A:Asp1814.99
AsN A:Asp1814.07
AsCB A:Asp1814.59
AsOD2 A:Asp1814.63
AsC A:Asp1814.88
AsOD1 A:Asp1814.01
AsCG A:Asp1814.21
AsCA A:Asp1813.90
AsCB A:Caf2122.99
AsCE2 A:Caf2121.94
AsSG A:Caf2122.25
AsO1 A:Caf2121.95
AsAS A:Caf2120.00
AsC A:Caf2124.52
AsCE1 A:Caf2121.97
AsCA A:Caf2123.93
AsCB A:Thr2144.59
AsOG1 A:Thr2144.53
AsO A:Hoh21574.78
AsO A:Hoh21613.81

interactive model:




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