Arsenic in the structure of Crystal Structure of An Autoimmune Complex Between A Human Igm Rheumatoid Factor And IGG1 Fc Reveals A Novel Fc Epitope and Evidence For Affinity Maturation (pdb 2j6e)

The binding sites of Arsenic atom in the structure of Crystal Structure of An Autoimmune Complex Between A Human Igm Rheumatoid Factor And IGG1 Fc Reveals A Novel Fc Epitope and Evidence For Affinity Maturation (pdb code 2j6e). This binding sites where shown with 5.0 Angstroms radius around Arsenic atom. The 2j6e structure was solved by S.DUQUERROY, E.A.STURA, S.BRESSANELLI, H.BROWNE, D.BEALE, M.HAMON, P.CASALI, M.-C.VANEY, F.A.REY, B.J.SUTTON, M.J.TAUSSIG, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 25.0-3.0 Space group C121 a (A) 241.980 b (A) 75.610 c (A) 102.400 alpha (°) 90.00 beta (°) 91.13 gamma (°) 90.00 Rfactor (%) 22.34 Rfree (%) 28.77 Arsenic Binding Sites: Arsenic binding site 1 out of 1 in 2j6e Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Arsenic in the PDB 2j6e. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Arsenic atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Glu345, A: His433, H: Asn56, A: Zn1446, A: Cac1447, conact list: Atom Atom Distance (A) As OE1 A:Glu345 3.89 As OE2 A:Glu345 3.85 As CD A:Glu345 4.16 As NE2 A:His433 4.30 As CE1 A:His433 4.32 As ND2 H:Asn56 4.91 As ZN A:Zn1446 2.96 As O1 A:Cac1447 1.50 As O2 A:Cac1447 1.50 As AS A:Cac1447 0.00 As C2 A:Cac1447 1.78 As C1 A:Cac1447 1.78 interactive model: