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Atomistry » Arsenic » PDB 2xod-3g2f » 3d3p | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Arsenic » PDB 2xod-3g2f » 3d3p » |
Arsenic in PDB 3d3p: Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine InhibitorEnzymatic activity of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
All present enzymatic activity of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor, PDB code: 3d3p
was solved by
D.O.Somers,
M.Neu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3d3p:
The structure of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor also contains other interesting chemical elements:
Arsenic Binding Sites:
The binding sites of Arsenic atom in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
(pdb code 3d3p). This binding sites where shown within
5.0 Angstroms radius around Arsenic atom.
In total 4 binding sites of Arsenic where determined in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor, PDB code: 3d3p: Jump to Arsenic binding site number: 1; 2; 3; 4; Arsenic binding site 1 out of 4 in 3d3pGo back to![]() ![]()
Arsenic binding site 1 out
of 4 in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
![]() Mono view ![]() Stereo pair view
Arsenic binding site 2 out of 4 in 3d3pGo back to![]() ![]()
Arsenic binding site 2 out
of 4 in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
![]() Mono view ![]() Stereo pair view
Arsenic binding site 3 out of 4 in 3d3pGo back to![]() ![]()
Arsenic binding site 3 out
of 4 in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
![]() Mono view ![]() Stereo pair view
Arsenic binding site 4 out of 4 in 3d3pGo back to![]() ![]()
Arsenic binding site 4 out
of 4 in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.N.Hamblin,
T.D.Angell,
S.P.Ballantine,
C.M.Cook,
A.W.Cooper,
J.Dawson,
C.J.Delves,
P.S.Jones,
M.Lindvall,
F.S.Lucas,
C.J.Mitchell,
M.Y.Neu,
L.E.Ranshaw,
Y.E.Solanke,
D.O.Somers,
J.O.Wiseman.
Pyrazolopyridines As A Novel Structural Class of Potent and Selective PDE4 Inhibitors. Bioorg.Med.Chem.Lett. V. 18 4237 2008.
Page generated: Sun Jul 6 23:20:24 2025
ISSN: ISSN 0960-894X PubMed: 18539455 DOI: 10.1016/J.BMCL.2008.05.052 |
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