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Atomistry » Arsenic » PDB 4cx1-4j8m » 4d36 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Arsenic » PDB 4cx1-4j8m » 4d36 » |
Arsenic in PDB 4d36: Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-AmineEnzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine
All present enzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine, PDB code: 4d36
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4d36:
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine also contains other interesting chemical elements:
Arsenic Binding Sites:
The binding sites of Arsenic atom in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine
(pdb code 4d36). This binding sites where shown within
5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine, PDB code: 4d36: Jump to Arsenic binding site number: 1; 2; Arsenic binding site 1 out of 2 in 4d36Go back to Arsenic Binding Sites List in 4d36
Arsenic binding site 1 out
of 2 in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine
Mono view Stereo pair view
Arsenic binding site 2 out of 2 in 4d36Go back to Arsenic Binding Sites List in 4d36
Arsenic binding site 2 out
of 2 in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N-2-(2-(1H-Imidazol-1-Yl)Pyrimidin- 4-Yl)Ethyl-3-(3-Chlorophenyl)Propan-1-Amine
Mono view Stereo pair view
Reference:
P.Mukherjee,
H.Li,
I.F.Sevrioukova,
G.Chreifi,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Novel 2,4-Disubstituted Pyrimidines As Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem. 2014.
Page generated: Wed Jul 10 12:05:37 2024
ISSN: ESSN 1520-4804 PubMed: 25489882 DOI: 10.1021/JM501719E |
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