Arsenic in PDB 4ikb: Crystal Structure of SNX11 Px Domain

The structure of Crystal Structure of SNX11 Px Domain, PDB code: 4ikb was solved by J.Xu, T.Xu, J.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.12 / 1.78
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.480, 38.740, 73.460, 90.00, 101.13, 90.00
R / Rfree (%)	16.9 / 22.1

The structure of Crystal Structure of SNX11 Px Domain also contains other interesting chemical elements:

Chlorine	(Cl)	3 atoms
Sodium	(Na)	2 atoms

The binding sites of Arsenic atom in the Crystal Structure of SNX11 Px Domain (pdb code 4ikb). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 3 binding sites of Arsenic where determined in the Crystal Structure of SNX11 Px Domain, PDB code: 4ikb:
Jump to Arsenic binding site number: 1; 2; 3;

Arsenic binding site 1 out of 3 in the Crystal Structure of SNX11 Px Domain


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of SNX11 Px Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:As55 b:16.9 occ:1.00 AS A:CAS55 0.0 16.9 1.0 CE2 A:CAS55 1.9 17.0 1.0 CE1 A:CAS55 2.0 16.0 1.0 SG A:CAS55 2.2 15.5 1.0 CB A:CAS55 3.2 12.8 1.0 O A:CAS55 3.6 10.6 1.0 C A:CAS55 3.8 10.4 1.0 CA A:CAS55 4.1 11.5 1.0 N A:VAL56 4.6 9.9 1.0 CD A:LYS39 4.7 16.7 1.0

Arsenic binding site 2 out of 3 in the Crystal Structure of SNX11 Px Domain


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of SNX11 Px Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:As138 b:22.8 occ:1.00 AS A:CAS138 0.0 22.8 1.0 CE2 A:CAS138 2.0 22.8 1.0 CE1 A:CAS138 2.0 22.8 1.0 SG A:CAS138 2.2 18.7 1.0 CB A:CAS138 3.2 16.2 1.0 CA A:CAS138 3.6 15.0 1.0 CD2 A:LEU143 3.9 28.5 1.0 CL A:CL211 4.0 45.6 1.0 O A:CAS138 4.2 13.3 1.0 CB A:LEU143 4.3 29.3 1.0 C A:CAS138 4.3 15.2 1.0 CG A:LEU143 4.7 28.8 1.0 N A:CAS138 4.9 14.0 1.0

Arsenic binding site 3 out of 3 in the Crystal Structure of SNX11 Px Domain


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Crystal Structure of SNX11 Px Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:As55 b:28.1 occ:1.00 AS B:CAS55 0.0 28.1 1.0 CE2 B:CAS55 1.9 26.8 1.0 CE1 B:CAS55 1.9 29.6 1.0 SG B:CAS55 2.3 23.4 1.0 CB B:CAS55 3.3 17.4 1.0 O B:CAS55 3.6 14.8 1.0 C B:CAS55 3.8 14.0 1.0 CA B:CAS55 4.1 15.7 1.0 N B:VAL56 4.5 12.5 1.0 O B:HOH315 4.5 17.4 1.0 O7 B:PE5206 4.8 36.7 1.0 CA B:VAL56 5.0 11.5 1.0

J.Xu, T.Xu, J.Liu. Structure of Sorting Nexin 11 (SNX11) Reveals A Novel Extended Px Domain (Pxe Domain) Critical For the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation To Be Published.