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Atomistry » Arsenic » PDB 4mwd-4uha » 4n07 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Arsenic » PDB 4mwd-4uha » 4n07 » |
Arsenic in PDB 4n07: Crystal Structure of the GLUA2 Ligand-Binding Domain (S1S2J-L483Y- N754S) in Complex with Glutamate and Bpam-344 at 1.87 A ResolutionProtein crystallography data
The structure of Crystal Structure of the GLUA2 Ligand-Binding Domain (S1S2J-L483Y- N754S) in Complex with Glutamate and Bpam-344 at 1.87 A Resolution, PDB code: 4n07
was solved by
A.B.Noerholm,
K.Frydenvang,
J.S.Kastrup,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4n07:
The structure of Crystal Structure of the GLUA2 Ligand-Binding Domain (S1S2J-L483Y- N754S) in Complex with Glutamate and Bpam-344 at 1.87 A Resolution also contains other interesting chemical elements:
Arsenic Binding Sites:
The binding sites of Arsenic atom in the Crystal Structure of the GLUA2 Ligand-Binding Domain (S1S2J-L483Y- N754S) in Complex with Glutamate and Bpam-344 at 1.87 A Resolution
(pdb code 4n07). This binding sites where shown within
5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the Crystal Structure of the GLUA2 Ligand-Binding Domain (S1S2J-L483Y- N754S) in Complex with Glutamate and Bpam-344 at 1.87 A Resolution, PDB code: 4n07: Arsenic binding site 1 out of 1 in 4n07Go back to![]() ![]()
Arsenic binding site 1 out
of 1 in the Crystal Structure of the GLUA2 Ligand-Binding Domain (S1S2J-L483Y- N754S) in Complex with Glutamate and Bpam-344 at 1.87 A Resolution
![]() Mono view ![]() Stereo pair view
Reference:
A.B.Nrholm,
P.Francotte,
L.Olsen,
C.Krintel,
K.Frydenvang,
E.Goffin,
S.Challal,
L.Danober,
I.Botez-Pop,
P.Lestage,
B.Pirotte,
J.S.Kastrup.
Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GLUA2-Positive Allosteric Modulators with A 3,4-Dihydro-2H-1,2,4-Benzothiadiazine 1,1-Dioxide Scaffold. J.Med.Chem. V. 56 8736 2013.
Page generated: Sun Jul 6 23:53:35 2025
ISSN: ISSN 0022-2623 PubMed: 24131202 DOI: 10.1021/JM4012092 |
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