Atomistry » Arsenic » PDB 4mwd-4uha » 4nse
Atomistry »
  Arsenic »
    PDB 4mwd-4uha »
      4nse »

Arsenic in PDB 4nse: Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex

Enzymatic activity of Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex

All present enzymatic activity of Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex:
1.14.13.39;

Protein crystallography data

The structure of Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex, PDB code: 4nse was solved by C.S.Raman, H.Li, P.Martasek, V.Kral, B.S.S.Masters, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.95
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 57.660, 106.100, 155.750, 90.00, 90.00, 90.00
R / Rfree (%) 21.2 / 26

Other elements in 4nse:

The structure of Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex also contains other interesting chemical elements:

Iron (Fe) 2 atoms
Zinc (Zn) 1 atom

Arsenic Binding Sites:

The binding sites of Arsenic atom in the Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex (pdb code 4nse). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex, PDB code: 4nse:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in 4nse

Go back to Arsenic Binding Sites List in 4nse
Arsenic binding site 1 out of 2 in the Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As950

b:63.2
occ:1.00
AS A:CAC950 0.0 63.2 1.0
C2 A:CAC950 1.8 53.7 1.0
C1 A:CAC950 1.8 46.1 1.0
SG A:CYS384 2.3 42.0 1.0
CB A:CYS384 3.3 34.0 1.0
CA A:CYS384 3.9 28.8 1.0
CE3 A:TRP324 4.5 28.6 1.0
O A:HOH984 4.6 28.4 1.0
CD1 A:LEU328 4.7 28.4 1.0
N A:CYS384 4.7 30.8 1.0
CD2 A:TRP324 4.8 29.9 1.0
C A:CYS384 5.0 28.4 1.0

Arsenic binding site 2 out of 2 in 4nse

Go back to Arsenic Binding Sites List in 4nse
Arsenic binding site 2 out of 2 in the Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Bovine Endothelial Nitric Oxide Synthase, H4B-Free, L-Arg Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:As950

b:72.3
occ:1.00
AS B:CAC950 0.0 72.3 1.0
C1 B:CAC950 1.8 71.2 1.0
C2 B:CAC950 1.8 67.8 1.0
SG B:CYS384 2.3 59.7 1.0
CB B:CYS384 3.1 50.1 1.0
CA B:CYS384 3.6 48.8 1.0
CE3 B:TRP324 4.3 50.4 1.0
CD2 B:TRP324 4.5 51.7 1.0
N B:CYS384 4.5 46.8 1.0
C B:CYS384 4.7 48.7 1.0
CB B:TRP324 4.7 46.9 1.0
CG B:TRP324 4.7 50.7 1.0
O B:CYS384 4.7 50.8 1.0
CZ3 B:TRP324 4.9 47.4 1.0

Reference:

C.S.Raman, H.Li, P.Martasek, V.Kral, B.S.Masters, T.L.Poulos. Crystal Structure of Constitutive Endothelial Nitric Oxide Synthase: A Paradigm For Pterin Function Involving A Novel Metal Center. Cell(Cambridge,Mass.) V. 95 939 1998.
ISSN: ISSN 0092-8674
PubMed: 9875848
DOI: 10.1016/S0092-8674(00)81718-3
Page generated: Tue Oct 27 16:53:54 2020

Last articles

Xe in 6AYK
Xe in 6QII
Xe in 6ASM
Xe in 5NSW
Xe in 6FY9
Xe in 5O1K
Xe in 5O27
Xe in 5M69
Xe in 5KPU
Xe in 5I63
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy