Arsenic in PDB 4pbe: Phosphotriesterase Variant REV6

All present enzymatic activity of Phosphotriesterase Variant REV6:
3.1.8.1;

The structure of Phosphotriesterase Variant REV6, PDB code: 4pbe was solved by E.Campbell, M.Kaltenbach, N.Tokuriki, C.J.Jackson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.59 / 1.51
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	85.638, 85.966, 89.188, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 24.9

The structure of Phosphotriesterase Variant REV6 also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Arsenic atom in the Phosphotriesterase Variant REV6 (pdb code 4pbe). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the Phosphotriesterase Variant REV6, PDB code: 4pbe:

Arsenic binding site 1 out of 1 in the Phosphotriesterase Variant REV6


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Phosphotriesterase Variant REV6 within 5.0Å range: probe atom residue distance (Å) B Occ A:As2403 b:26.0 occ:0.58 AS A:CAC2403 0.0 26.0 0.6 O1 A:CAC2403 1.7 10.2 0.6 O2 A:CAC2403 1.8 12.1 0.6 C1 A:CAC2403 2.0 21.1 0.6 C2 A:CAC2403 2.0 17.7 0.6 ZN A:ZN2402 2.8 17.2 1.0 ZN A:ZN2401 3.2 11.0 1.0 OQ1 A:KCX169 3.4 11.0 1.0 O A:HOH2674 3.7 42.6 1.0 OD2 A:ASP301 3.8 11.9 1.0 OQ2 A:KCX169 3.9 10.6 1.0 CX A:KCX169 4.1 12.1 1.0 NE1 A:TRP131 4.1 14.7 1.0 OD1 A:ASP301 4.2 11.3 1.0 NE2 A:HIS230 4.3 12.0 1.0 O A:HOH2590 4.3 23.9 1.0 NE2 A:HIS57 4.3 11.2 1.0 CG A:ASP301 4.4 10.7 1.0 CZ2 A:TRP131 4.5 14.7 1.0 ND1 A:HIS201 4.5 18.1 1.0 CE2 A:TRP131 4.6 18.3 1.0 CE1 A:HIS230 4.8 14.6 1.0 NH1 A:ARG254 4.8 19.7 1.0 CE1 A:HIS201 4.9 17.1 1.0 CE1 A:HIS57 4.9 9.0 1.0 NE2 A:HIS55 4.9 9.0 1.0

E.Campbell, M.Kaltenbach, N.Tokuriki, C.J.Jackson. Phosphotriesterase Variant REV6 To Be Published.