Arsenic in PDB 6rcq: PFRH5-Binding Monoclonal Antibody R5.011

The structure of PFRH5-Binding Monoclonal Antibody R5.011, PDB code: 6rcq was solved by D.W.G.Alanine, S.J.Draper, M.K.Higgins, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.80 / 2.28
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	47.858, 86.375, 127.409, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 22.7

The binding sites of Arsenic atom in the PFRH5-Binding Monoclonal Antibody R5.011 (pdb code 6rcq). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the PFRH5-Binding Monoclonal Antibody R5.011, PDB code: 6rcq:

Arsenic binding site 1 out of 1 in the PFRH5-Binding Monoclonal Antibody R5.011


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of PFRH5-Binding Monoclonal Antibody R5.011 within 5.0Å range: probe atom residue distance (Å) B Occ B:As302 b:0.4 occ:1.00 AS B:CAC302 0.0 0.4 1.0 O2 B:CAC302 1.7 0.3 1.0 O1 B:CAC302 1.7 0.4 1.0 C2 B:CAC302 2.0 1.0 1.0 C1 B:CAC302 2.0 0.9 1.0 OD2 B:ASP140 3.0 46.1 1.0 CE1 A:HIS179 3.2 42.0 1.0 NE2 A:HIS179 3.4 42.8 1.0 CG B:ASP140 3.8 41.9 1.0 OD1 B:ASP140 3.8 44.7 1.0 ND1 A:HIS179 4.3 43.4 1.0 CD2 A:HIS179 4.5 44.2 1.0 ND2 B:ASN171 4.8 48.0 1.0 CG A:HIS179 4.9 43.1 1.0

D.G.W.Alanine, D.Quinkert, R.Kumarasingha, S.Mehmood, F.R.Donnellan, N.K.Minkah, B.Dadonaite, A.Diouf, F.Galaway, S.E.Silk, A.Jamwal, J.M.Marshall, K.Miura, L.Foquet, S.C.Elias, G.M.Labbe, A.D.Douglas, J.Jin, R.O.Payne, J.J.Illingworth, D.J.Pattinson, D.Pulido, B.G.Williams, W.A.De Jongh, G.J.Wright, S.H.I.Kappe, C.V.Robinson, C.A.Long, B.S.Crabb, P.R.Gilson, M.K.Higgins, S.J.Draper. Human Antibodies That Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell V. 178 216 2019.
ISSN: ISSN 1097-4172
PubMed: 31204103
DOI: 10.1016/J.CELL.2019.05.025