Arsenic in PDB 6xu0: Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat

The structure of Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat, PDB code: 6xu0 was solved by S.Grazulis, M.Zaremba, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.44 / 1.90
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	51.909, 61.205, 103.092, 98.32, 104.96, 100.62
R / Rfree (%)	18.1 / 22.5

The structure of Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Potassium	(K)	1 atom

The binding sites of Arsenic atom in the Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat (pdb code 6xu0). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 3 binding sites of Arsenic where determined in the Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat, PDB code: 6xu0:
Jump to Arsenic binding site number: 1; 2; 3;

Arsenic binding site 1 out of 3 in the Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat within 5.0Å range: probe atom residue distance (Å) B Occ A:As502 b:157.4 occ:1.00 AS A:CAC502 0.0 157.4 1.0 O1 A:CAC502 1.8 125.3 1.0 O2 A:CAC502 1.8 159.2 1.0 C1 A:CAC502 2.0 111.0 1.0 C2 A:CAC502 2.0 111.4 1.0 CD2 A:TYR360 4.4 42.0 1.0 CG A:TYR360 4.6 40.3 1.0 CE2 A:TYR361 4.6 49.2 1.0 CE2 A:TYR360 4.7 48.8 1.0 OH A:TYR361 4.8 58.2 1.0 CD1 A:TYR360 4.9 45.7 1.0

Arsenic binding site 2 out of 3 in the Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat within 5.0Å range: probe atom residue distance (Å) B Occ A:As503 b:160.3 occ:1.00 AS A:CAC503 0.0 160.3 1.0 O2 A:CAC503 1.8 99.4 1.0 O1 A:CAC503 1.8 77.7 1.0 C1 A:CAC503 2.0 72.7 1.0 C2 A:CAC503 2.0 70.6 1.0 O A:GLY409 3.7 49.6 1.0 C A:GLY409 4.2 39.4 1.0 O A:GLY408 4.2 54.6 1.0 CD2 A:TYR410 4.5 54.5 1.0 N A:TYR410 4.5 36.3 1.0 CE2 A:TYR410 4.6 53.0 1.0 CA A:TYR410 4.6 41.3 1.0 CG A:TYR410 4.7 38.3 1.0 CZ A:TYR410 4.8 52.9 1.0 CD1 A:TYR410 4.9 42.9 1.0 CA A:GLY409 4.9 36.5 1.0 CE1 A:TYR410 5.0 55.3 1.0

Arsenic binding site 3 out of 3 in the Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'- Patcgtggccacgat within 5.0Å range: probe atom residue distance (Å) B Occ B:As503 b:138.3 occ:1.00 AS B:CAC503 0.0 138.3 1.0 O1 B:CAC503 1.8 91.2 1.0 O2 B:CAC503 1.8 86.0 1.0 C1 B:CAC503 2.0 62.1 1.0 C2 B:CAC503 2.0 58.9 1.0 O B:GLY408 4.1 60.7 1.0 O B:GLY409 4.2 45.0 1.0 O B:HOH622 4.4 46.0 1.0 O B:HOH609 4.4 70.8 1.0 C B:GLY409 4.4 42.5 1.0 CE1 B:TYR410 4.5 41.5 1.0 CD1 B:TYR410 4.6 38.1 1.0 CZ B:TYR410 4.6 41.1 1.0 NZ B:LYS125 4.7 62.1 1.0 CG B:TYR410 4.7 37.0 1.0 N B:TYR410 4.8 41.0 1.0 CE B:LYS125 4.8 73.7 1.0 CE2 B:TYR410 4.8 46.9 1.0 CD2 B:TYR410 4.8 40.2 1.0 CA B:TYR410 4.9 39.7 1.0

E.Golovinas, E.Manakova, G.Sasnauskas, M.Zaremba. Archaeoglobus Fulgidus Argonaute Protein with Dna Oligoduplex 5'-Patcgtggccacgat To Be Published.