Arsenic in PDB 6ype: Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain.

The structure of Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain., PDB code: 6ype was solved by J.Elegheert, A.J.Clayton, A.R.Aricescu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.69 / 1.45
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	121.220, 36.060, 92.170, 90.00, 97.47, 90.00
R / Rfree (%)	15.3 / 17.8

The structure of Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain. also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Arsenic atom in the Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain. (pdb code 6ype). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain., PDB code: 6ype:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain.


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain. within 5.0Å range: probe atom residue distance (Å) B Occ A:As502 b:20.5 occ:1.00 AS A:CAC502 0.0 20.5 1.0 O1 A:CAC502 1.7 21.0 1.0 O2 A:CAC502 1.7 21.0 1.0 C2 A:CAC502 2.0 20.8 1.0 C1 A:CAC502 2.0 20.7 1.0 CA A:CA500 3.6 9.0 1.0 CA A:CA501 3.7 9.0 1.0 O A:HOH763 3.8 35.5 1.0 OE2 A:GLU358 3.8 9.6 1.0 NE2 A:GLN370 3.8 13.0 1.0 OD1 A:ASP360 4.0 9.6 1.0 ND2 A:ASN280 4.1 10.2 1.0 OE1 A:GLU358 4.1 9.8 1.0 CD A:GLU358 4.1 12.7 1.0 O A:HOH698 4.6 36.4 1.0 O A:HOH746 4.6 13.1 1.0 O B:HOH666 4.6 21.5 1.0 OE1 A:GLN370 4.7 9.4 1.0 CD A:GLN370 4.7 12.7 1.0 OD1 A:ASN280 4.8 10.0 1.0 O A:HOH635 4.8 14.5 1.0 CZ3 A:TRP287 4.8 17.9 1.0 CG A:ASN280 4.9 7.7 1.0 CG A:ASP360 5.0 9.5 1.0

Arsenic binding site 2 out of 2 in the Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain.


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of the Human Neuronal Pentraxin 1 (NP1) Pentraxin (Ptx) Domain. within 5.0Å range: probe atom residue distance (Å) B Occ B:As502 b:15.8 occ:1.00 AS B:CAC502 0.0 15.8 1.0 O2 B:CAC502 1.7 15.9 1.0 O1 B:CAC502 1.7 16.0 1.0 C1 B:CAC502 2.0 15.8 1.0 C2 B:CAC502 2.0 15.8 1.0 CA B:CA500 3.6 9.6 1.0 OE1 B:GLU358 3.7 9.9 1.0 O B:HOH638 3.7 21.9 1.0 O B:HOH700 3.7 24.7 1.0 CA B:CA501 3.7 11.1 1.0 NE2 B:GLN370 3.8 14.2 1.0 CD B:GLU358 4.0 8.6 1.0 OE2 B:GLU358 4.1 9.7 1.0 OD1 B:ASP360 4.1 11.0 1.0 ND2 B:ASN280 4.2 10.8 1.0 O B:HOH668 4.6 33.8 1.0 OE1 B:GLN370 4.6 10.8 1.0 CD B:GLN370 4.7 11.9 1.0 OD1 B:ASN280 4.8 8.7 1.0 O B:HOH640 4.8 12.9 1.0 O B:HOH748 4.8 11.5 1.0 CG B:ASN280 4.9 9.3 1.0 CG B:GLU358 5.0 10.4 1.0

K.Suzuki, J.Elegheert, I.Song, H.Sasakura, O.Senkov, W.Kakegawa, A.J.Clayton, V.T.Chang, M.Ferrer-Ferrer, E.Miura, R.Kaushik, M.Ikeno, Y.Morioka, Y.Takeuchi, T.Shimada, S.Otsuka, S.Stoyanov, M.Watanabe, K.Takeuchi, A.Dityatev, A.R.Aricescu, M.Yuzaki. A Synthetic Synaptic Organizer Protein Restores Glutamatergic Neuronal Circuits. To Be Published.