Arsenic in PDB 6z3x: Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1

The structure of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1, PDB code: 6z3x was solved by E.Costanzi, P.Sormanni, S.Ricagno, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.34 / 1.74
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.718, 52.411, 99.176, 90, 90, 90
R / Rfree (%)	19.3 / 22

The structure of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Arsenic atom in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 (pdb code 6z3x). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 6 binding sites of Arsenic where determined in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1, PDB code: 6z3x:
Jump to Arsenic binding site number: 1; 2; 3; 4; 5; 6;

Arsenic binding site 1 out of 6 in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 within 5.0Å range: probe atom residue distance (Å) B Occ A:As301 b:68.6 occ:1.00 AS A:CAC301 0.0 68.6 1.0 O1 A:CAC301 1.7 83.4 1.0 O2 A:CAC301 1.7 71.1 1.0 C2 A:CAC301 2.0 68.9 1.0 C1 A:CAC301 2.0 67.8 1.0 O A:TYR61 3.7 25.1 1.0 O A:HOH411 3.9 30.3 1.0 NZ A:LYS66 4.0 39.5 1.0 CE A:LYS66 4.5 37.6 1.0 OD1 A:ASP63 4.6 40.3 1.0 C A:TYR61 4.9 22.8 1.0

Arsenic binding site 2 out of 6 in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 within 5.0Å range: probe atom residue distance (Å) B Occ B:As201 b:81.1 occ:0.75 AS B:CAC201 0.0 81.1 0.8 O1 B:CAC201 1.7 86.2 0.8 O2 B:CAC201 1.7 88.3 0.8 C2 B:CAC201 2.0 81.9 0.8 C1 B:CAC201 2.0 79.7 0.8 N B:SER129 4.3 76.5 1.0 O A:GLY120 4.4 28.4 1.0 O A:TRP119 4.5 28.1 1.0 O B:ASP130 4.7 79.8 1.0 CA B:SER128 4.7 28.5 1.0 O A:HOH425 4.9 28.9 1.0 C A:GLY120 5.0 22.6 1.0

Arsenic binding site 3 out of 6 in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 within 5.0Å range: probe atom residue distance (Å) B Occ B:As202 b:100.4 occ:0.74 AS B:CAC202 0.0 100.4 0.7 O2 B:CAC202 1.7 102.9 0.7 O1 B:CAC202 1.7 103.1 0.7 C2 B:CAC202 2.0 98.2 0.7 C1 B:CAC202 2.0 98.6 0.7 N B:GLY27 3.9 25.7 1.0 CA B:SER26 4.5 21.9 1.0 O B:PHE28 4.5 25.0 1.0 ND2 B:ASN78 4.6 25.7 1.0 C B:SER26 4.7 21.2 1.0 CA B:GLY27 4.8 28.7 1.0 N B:PHE28 4.8 27.0 1.0 CB B:SER26 5.0 30.9 1.0

Arsenic binding site 4 out of 6 in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 4 of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 within 5.0Å range: probe atom residue distance (Å) B Occ B:As203 b:70.2 occ:1.00 AS B:CAC203 0.0 70.2 1.0 O2 B:CAC203 1.7 80.9 1.0 O1 B:CAC203 1.7 72.6 1.0 C2 B:CAC203 2.0 72.2 1.0 C1 B:CAC203 2.0 73.5 1.0 NA B:NA207 3.3 63.4 1.0 OG1 B:THR75 3.6 31.2 1.0 N B:THR75 4.1 20.6 1.0 O1 B:CAC205 4.3 70.8 0.7 CG2 B:THR75 4.6 29.9 1.0 OD1 B:ASP74 4.6 32.6 1.0 CB B:THR75 4.6 28.7 1.0 CA B:ASP74 4.7 22.9 1.0 O2 B:CAC205 4.7 72.5 0.7 O B:ALA73 4.8 27.6 1.0 C B:ASP74 4.9 27.1 1.0 CA B:THR75 4.9 22.5 1.0

Arsenic binding site 5 out of 6 in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 5 of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 within 5.0Å range: probe atom residue distance (Å) B Occ B:As205 b:73.8 occ:0.70 AS B:CAC205 0.0 73.8 0.7 O1 B:CAC205 1.7 70.8 0.7 O2 B:CAC205 1.7 72.5 0.7 C2 B:CAC205 1.9 65.4 0.7 C1 B:CAC205 2.0 72.3 0.7 O2 B:CAC203 4.2 80.9 1.0 CA B:GLY57 4.7 23.7 1.0 O B:SER56 4.7 28.5 1.0 N B:GLY57 4.8 25.8 1.0 C B:SER56 4.9 29.4 1.0 O B:HOH348 4.9 36.1 1.0 C2 B:CAC203 5.0 72.2 1.0

Arsenic binding site 6 out of 6 in the Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 6 of Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 within 5.0Å range: probe atom residue distance (Å) B Occ B:As206 b:76.1 occ:0.57 AS B:CAC206 0.0 76.1 0.6 O2 B:CAC206 1.7 77.2 0.6 O1 B:CAC206 1.7 66.5 0.6 C1 B:CAC206 2.0 76.2 0.6 C2 B:CAC206 2.0 78.0 0.6 OH B:TYR61 3.7 26.3 1.0 O B:HOH312 3.7 33.0 1.0 OG1 B:THR59 4.0 28.0 1.0 CE2 B:TYR61 4.3 31.7 1.0 CZ B:TYR61 4.4 29.1 1.0 CG2 B:THR70 4.6 24.7 1.0 CG2 B:THR59 4.8 27.0 1.0 CB B:THR59 4.9 25.1 1.0

E.Costanzi, P.Sormanni, S.Ricagno. Crystal Structure of the Designed Antibody Desab-Anti-Hsa-P1 To Be Published.