Arsenic in PDB 7kg8: Structure of Human Parg Complexed with Parg-061

All present enzymatic activity of Structure of Human Parg Complexed with Parg-061:
3.2.1.143;

The structure of Structure of Human Parg Complexed with Parg-061, PDB code: 7kg8 was solved by C.A.Brosey, L.P.F.Balapiti-Modarage, L.S.Warden, D.E.Jones, Z.Ahmed, J.A.Tainer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.33 / 1.43
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	66.408, 89.201, 93.877, 90, 90, 90
R / Rfree (%)	17.2 / 19.2

The binding sites of Arsenic atom in the Structure of Human Parg Complexed with Parg-061 (pdb code 7kg8). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the Structure of Human Parg Complexed with Parg-061, PDB code: 7kg8:

Arsenic binding site 1 out of 1 in the Structure of Human Parg Complexed with Parg-061


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Structure of Human Parg Complexed with Parg-061 within 5.0Å range: probe atom residue distance (Å) B Occ A:As1008 b:74.0 occ:1.00 AS A:CAC1008 0.0 74.0 1.0 O2 A:CAC1008 1.7 54.4 1.0 O1 A:CAC1008 1.7 46.4 1.0 C1 A:CAC1008 1.9 33.3 1.0 C2 A:CAC1008 2.0 45.0 1.0 HH12 A:ARG941 2.7 53.3 1.0 HH22 A:ARG941 3.1 54.7 1.0 NH1 A:ARG941 3.5 44.4 1.0 NH2 A:ARG941 3.8 45.6 1.0 CZ A:ARG941 4.1 37.6 1.0 HH11 A:ARG941 4.1 53.3 1.0 HD22 A:ASN942 4.3 47.1 1.0 HH21 A:ARG941 4.5 54.7 1.0 OD1 A:ASN942 4.8 48.1 1.0

C.A.Brosey, J.H.Houl, P.Katsonis, L.P.F.Balapiti-Modarage, S.Bommagani, A.Arvai, D.Moiani, A.Bacolla, T.Link, L.S.Warden, O.Lichtarge, D.E.Jones, Z.Ahmed, J.A.Tainer. Targeting Sars-Cov-2 NSP3 Macrodomain Structure with Insights From Human Poly(Adp-Ribose) Glycohydrolase (Parg) Structures with Inhibitors. Prog.Biophys.Mol.Biol. 2021.
ISSN: ISSN 0079-6107
PubMed: 33636189
DOI: 10.1016/J.PBIOMOLBIO.2021.02.002