Arsenic in PDB 7l2c: Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd)

The structure of Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd), PDB code: 7l2c was solved by G.Cerutti, E.R.Reddem, L.Shapiro, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	88.03 / 3.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.791, 115.785, 137.606, 90, 99.97, 90
R / Rfree (%)	21.6 / 27.2

The structure of Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd) also contains other interesting chemical elements:

Calcium

(Ca)

39 atoms

The binding sites of Arsenic atom in the Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd) (pdb code 7l2c). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd), PDB code: 7l2c:

Arsenic binding site 1 out of 1 in the Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd)


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystallographic Structure of Neutralizing Antibody 2-51 in Complex with Sars-Cov-2 Spike N-Terminal Domain (Ntd) within 5.0Å range: probe atom residue distance (Å) B Occ A:As417 b:172.4 occ:1.00 AS A:CAC417 0.0 172.4 1.0 O1 A:CAC417 1.7 100.2 1.0 O2 A:CAC417 1.7 77.1 1.0 C2 A:CAC417 2.0 109.7 1.0 C1 A:CAC417 2.0 95.3 1.0 O A:ASN137 4.0 86.2 1.0 O A:CYS136 4.3 89.8 1.0 CD1 A:LEU110 4.4 75.6 1.0 CG2 A:VAL83 4.4 73.5 1.0 CA A:ASN137 4.5 90.6 1.0 C A:ASN137 4.6 86.7 1.0 NE2 A:GLN239 4.6 73.7 1.0 CB A:LEU110 4.7 75.7 1.0

G.Cerutti, Y.Guo, T.Zhou, J.Gorman, M.Lee, M.Rapp, E.R.Reddem, J.Yu, F.Bahna, J.Bimela, Y.Huang, P.S.Katsamba, L.Liu, M.S.Nair, R.Rawi, A.S.Olia, P.Wang, G.Chuang, D.D.Ho, Z.Sheng, P.D.Kwong, L.Shapiro. Potent Sars-Cov-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target A Single Supersite Biorxiv 2021.
DOI: 10.1101/2021.01.10.426120