Arsenic in PDB 8old: Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains

The structure of Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains, PDB code: 8old was solved by E.N.Manakova, M.Zaremba, S.Grazulis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.63 / 1.85
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	42.033, 57.843, 61.622, 73.94, 89.56, 89.75
R / Rfree (%)	17.9 / 21.8

The structure of Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains also contains other interesting chemical elements:

Sodium	(Na)	1 atom
Chlorine	(Cl)	2 atoms

The binding sites of Arsenic atom in the Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains (pdb code 8old). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 3 binding sites of Arsenic where determined in the Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains, PDB code: 8old:
Jump to Arsenic binding site number: 1; 2; 3;

Arsenic binding site 1 out of 3 in the Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains within 5.0Å range: probe atom residue distance (Å) B Occ B:As301 b:167.3 occ:1.00 AS B:CAC301 0.0 167.3 1.0 O2 B:CAC301 1.7 163.2 1.0 O1 B:CAC301 1.7 162.8 1.0 C1 B:CAC301 2.0 160.3 1.0 C2 B:CAC301 2.0 159.9 1.0 CG B:TYR64 4.3 33.6 1.0 CD2 B:TYR64 4.5 29.6 1.0 CD1 B:TYR64 4.5 34.8 1.0 OE1 B:GLU94 4.7 38.0 1.0 CB B:TYR64 4.7 31.9 1.0 OE2 B:GLU94 4.8 40.4 1.0 CD B:GLU94 4.8 37.8 1.0 CE2 B:TYR64 4.8 36.9 1.0 CE1 B:TYR64 4.9 38.6 1.0

Arsenic binding site 2 out of 3 in the Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:As301 b:157.7 occ:1.00 AS C:CAC301 0.0 157.7 1.0 O1 C:CAC301 1.7 140.1 1.0 O2 C:CAC301 1.7 152.0 1.0 C1 C:CAC301 2.0 143.4 1.0 C2 C:CAC301 2.0 147.3 1.0 NH2 C:ARG188 4.5 53.4 1.0 CD1 C:LEU207 4.9 31.2 1.0

Arsenic binding site 3 out of 3 in the Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Crystal Structure of Archaeoglobus Fulgidus Afago-N Protein Representing N-L1-L2 Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:As302 b:147.8 occ:1.00 AS C:CAC302 0.0 147.8 1.0 O1 C:CAC302 1.7 148.2 1.0 O2 C:CAC302 1.7 130.8 1.0 C2 C:CAC302 2.0 139.2 1.0 C1 C:CAC302 2.0 138.6 1.0 NE2 C:HIS136 4.3 46.1 1.0 CD1 C:TRP138 4.5 42.7 1.0 CG C:TRP138 4.6 37.7 1.0 CD2 C:HIS136 4.8 42.0 1.0 NE1 C:TRP138 4.8 44.1 1.0 CD2 C:TRP138 4.9 37.4 1.0 CB C:TRP138 4.9 36.6 1.0

E.Manakova, E.Golovinas, R.Poceviciute, G.Sasnauskas, A.Silanskas, D.Rutkauskas, M.Jankunec, E.Zagorskaite, E.Jurgelaitis, A.Grybauskas, C.Venclovas, M.Zaremba. The Missing Part: the Archaeoglobus Fulgidus Argonaute Forms A Functional Heterodimer with An N-L1-L2 Domain Protein. Nucleic Acids Res. 2024.
ISSN: ESSN 1362-4962
PubMed: 38197228
DOI: 10.1093/NAR/GKAD1241