Arsenic in PDB 9b8u: Crystal Structure of Crx-RET4 Oligonucleotide Complex

The structure of Crystal Structure of Crx-RET4 Oligonucleotide Complex, PDB code: 9b8u was solved by D.Srivastava, N.O.Artemyev, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.67 / 2.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	109.597, 75.494, 97.229, 90, 120.25, 90
R / Rfree (%)	24.9 / 24.9

The structure of Crystal Structure of Crx-RET4 Oligonucleotide Complex also contains other interesting chemical elements:

Sodium	(Na)	2 atoms
Potassium	(K)	3 atoms

The binding sites of Arsenic atom in the Crystal Structure of Crx-RET4 Oligonucleotide Complex (pdb code 9b8u). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Crystal Structure of Crx-RET4 Oligonucleotide Complex, PDB code: 9b8u:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Crystal Structure of Crx-RET4 Oligonucleotide Complex


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of Crx-RET4 Oligonucleotide Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:As201 b:155.8 occ:1.00 AS A:CAC201 0.0 155.8 1.0 O2 A:CAC201 1.7 123.8 1.0 O1 A:CAC201 1.7 104.0 1.0 C1 A:CAC201 2.0 154.5 1.0 C2 A:CAC201 2.0 121.5 1.0 CB A:ALA68 3.7 76.6 1.0 O A:HOH306 4.2 88.2 1.0 CB A:ASP65 4.3 105.2 1.0 N A:ASP65 4.4 75.0 1.0 O A:HOH304 4.5 54.2 1.0 N A:ALA68 4.6 78.0 1.0 CA A:ALA68 4.8 56.9 1.0 CA A:ASP65 4.9 95.3 1.0

Arsenic binding site 2 out of 2 in the Crystal Structure of Crx-RET4 Oligonucleotide Complex


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure of Crx-RET4 Oligonucleotide Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:As101 b:198.8 occ:1.00 AS E:CAC101 0.0 198.8 1.0 O2 E:CAC101 1.7 142.4 1.0 O1 E:CAC101 1.7 128.4 1.0 C1 E:CAC101 2.0 164.4 1.0 C2 E:CAC101 2.0 147.9 1.0 O4' E:DG35 4.5 86.2 1.0 K F:K102 4.5 106.0 1.0 C2' E:DG34 4.6 97.8 1.0 C4' E:DG35 4.7 94.3 1.0 C5' E:DG35 4.8 90.0 1.0

D.Srivastava, N.O.Artemyev. Molecular Basis of Crx Homeodomain/Dna Binding and Stoichiometry at the RET4 Cis-Regulatory Element in Rhodopsin Promoter To Be Published.