Arsenic in PDB 2h5k: Crystal Structure of Complex Between the Domain-Swapped Dimeric GRB2 SH2 Domain and Shc-Derived Ligand, Ac-Nh-Ptyr-Val-Asn-NH2

The structure of Crystal Structure of Complex Between the Domain-Swapped Dimeric GRB2 SH2 Domain and Shc-Derived Ligand, Ac-Nh-Ptyr-Val-Asn-NH2, PDB code: 2h5k was solved by A.P.Benfield, B.B.Whiddon, S.F.Martin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.25
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	94.859, 94.859, 139.236, 90.00, 90.00, 120.00
R / Rfree (%)	24.7 / 30

The binding sites of Arsenic atom in the Crystal Structure of Complex Between the Domain-Swapped Dimeric GRB2 SH2 Domain and Shc-Derived Ligand, Ac-Nh-Ptyr-Val-Asn-NH2 (pdb code 2h5k). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the Crystal Structure of Complex Between the Domain-Swapped Dimeric GRB2 SH2 Domain and Shc-Derived Ligand, Ac-Nh-Ptyr-Val-Asn-NH2, PDB code: 2h5k:

Arsenic binding site 1 out of 1 in the Crystal Structure of Complex Between the Domain-Swapped Dimeric GRB2 SH2 Domain and Shc-Derived Ligand, Ac-Nh-Ptyr-Val-Asn-NH2


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure of Complex Between the Domain-Swapped Dimeric GRB2 SH2 Domain and Shc-Derived Ligand, Ac-Nh-Ptyr-Val-Asn-NH2 within 5.0Å range: probe atom residue distance (Å) B Occ B:As10 b:59.5 occ:1.00 AS B:CAC10 0.0 59.5 1.0 O1 B:CAC10 1.5 64.3 1.0 C1 B:CAC10 1.5 63.1 1.0 C2 B:CAC10 1.5 63.8 1.0 O2 B:CAC10 1.5 64.3 1.0 NH1 B:ARG86 3.6 58.4 1.0 NH2 B:ARG86 3.8 58.0 1.0 OG B:SER96 3.8 39.8 1.0 CZ B:ARG86 4.2 58.0 1.0 CB B:SER96 4.2 40.8 1.0 O B:HOH7 4.3 27.4 1.0 OG B:SER88 4.4 73.3 1.0 N B:GLU89 4.6 75.7 1.0 CA B:SER88 4.6 72.4 1.0 CB B:SER88 4.6 72.4 1.0 CD B:ARG67 4.9 72.4 1.0

A.P.Benfield, B.B.Whiddon, J.H.Clements, S.F.Martin. Structural and Energetic Aspects of GRB2-SH2 Domain-Swapping. Arch.Biochem.Biophys. V. 462 47 2007.
ISSN: ISSN 0003-9861
PubMed: 17466257
DOI: 10.1016/J.ABB.2007.03.010