Arsenic in PDB 4gnj: Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase

All present enzymatic activity of Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase:
5.3.1.1;

The structure of Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase, PDB code: 4gnj was solved by B.Kuaprasert, P.Riangrungroj, W.Pornthanakasem, W.Suginta, M.Mungthin, S.Leelayoova, U.Leartsakulpanich, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.61 / 1.93
Space group	P 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	39.580, 78.790, 83.160, 90.00, 101.15, 90.00
R / Rfree (%)	15.1 / 19.9

The structure of Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Arsenic atom in the Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase (pdb code 4gnj). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase, PDB code: 4gnj:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase within 5.0Å range: probe atom residue distance (Å) B Occ A:As301 b:54.5 occ:1.00 SG A:CYS57 2.4 20.4 1.0 CB A:CYS57 3.0 15.3 1.0 CG B:GLN193 3.6 25.5 1.0 N B:TRP194 4.0 15.9 1.0 CB B:GLN193 4.0 18.5 1.0 C B:GLN193 4.1 16.7 1.0 O A:LYS55 4.2 13.6 1.0 CA B:TRP194 4.3 15.9 1.0 O B:GLN193 4.3 16.2 1.0 CA A:CYS57 4.3 14.4 1.0 N A:CYS57 4.5 13.8 1.0 O A:HOH549 4.7 26.7 1.0 ND2 A:ASN30 4.7 10.7 1.0 O A:HOH547 4.7 22.5 1.0 CB B:TRP194 4.7 14.9 1.0 CA B:GLN193 4.7 17.8 1.0 CD B:GLN193 4.8 30.6 1.0 O B:LEU190 4.8 15.7 1.0 C A:LYS55 5.0 13.7 1.0

Arsenic binding site 2 out of 2 in the Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase within 5.0Å range: probe atom residue distance (Å) B Occ B:As301 b:28.1 occ:1.00 SG B:CYS57 2.2 19.6 1.0 CB B:CYS57 3.2 16.9 1.0 O B:CYS57 3.6 19.2 1.0 C B:CYS57 4.1 17.1 1.0 CA B:CYS57 4.2 16.8 1.0 N B:ASN58 4.9 16.3 1.0 O B:ASN30 4.9 19.3 1.0

B.Kuaprasert, P.Riangrungroj, W.Pornthanakasem, W.Suginta, M.Mungthin, S.Leelayoova, U.Leartsakulpanich. Crystal Structure Analysis of Leishmania Siamensis Triosephosphate Isomerase To Be Published.