Atomistry » Arsenic » PDB 4j9t-4mwc » 4llh
Atomistry »
  Arsenic »
    PDB 4j9t-4mwc »
      4llh »

Arsenic in PDB 4llh: Substrate Bound Outward-Open State of the Symporter Betp

Protein crystallography data

The structure of Substrate Bound Outward-Open State of the Symporter Betp, PDB code: 4llh was solved by C.Perez, B.Faust, C.Ziegler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.30 / 2.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 115.470, 129.690, 164.650, 90.00, 90.00, 90.00
R / Rfree (%) 24 / 29

Other elements in 4llh:

The structure of Substrate Bound Outward-Open State of the Symporter Betp also contains other interesting chemical elements:

Chlorine (Cl) 1 atom
Sodium (Na) 2 atoms

Arsenic Binding Sites:

The binding sites of Arsenic atom in the Substrate Bound Outward-Open State of the Symporter Betp (pdb code 4llh). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 3 binding sites of Arsenic where determined in the Substrate Bound Outward-Open State of the Symporter Betp, PDB code: 4llh:
Jump to Arsenic binding site number: 1; 2; 3;

Arsenic binding site 1 out of 3 in 4llh

Go back to Arsenic Binding Sites List in 4llh
Arsenic binding site 1 out of 3 in the Substrate Bound Outward-Open State of the Symporter Betp


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Substrate Bound Outward-Open State of the Symporter Betp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:As601

b:0.8
occ:1.00
AS1 A:1Y8601 0.0 0.8 1.0
C8 A:1Y8601 1.8 44.7 1.0
C7 A:1Y8601 1.8 0.2 1.0
C6 A:1Y8601 1.8 0.3 1.0
C5 A:1Y8601 2.0 0.4 1.0
C4 A:1Y8601 2.9 95.5 1.0
O6 A:1Y8601 3.4 95.3 1.0
CD2 A:TRP377 4.1 77.8 1.0
CZ3 A:TRP374 4.1 61.1 1.0
CE2 A:TRP373 4.2 88.5 1.0
CE2 A:TRP377 4.2 80.8 1.0
CZ2 A:TRP373 4.2 91.7 1.0
CE3 A:TRP377 4.3 75.1 1.0
CE3 A:TRP374 4.4 62.3 1.0
CH2 A:TRP374 4.4 61.8 1.0
CD2 A:TRP373 4.4 85.2 1.0
CG A:TRP377 4.4 72.9 1.0
CH2 A:TRP373 4.5 90.7 1.0
CZ2 A:TRP377 4.5 78.9 1.0
NE1 A:TRP373 4.5 84.9 1.0
NE1 A:TRP377 4.6 80.9 1.0
CZ3 A:TRP377 4.6 76.5 1.0
O A:GLY149 4.6 78.1 1.0
CD1 A:TRP377 4.7 78.2 1.0
CE3 A:TRP373 4.7 86.2 1.0
CZ3 A:TRP373 4.7 87.3 1.0
CH2 A:TRP377 4.7 77.9 1.0
N A:GLY151 4.8 89.1 1.0
OH A:TYR197 4.8 83.4 1.0
CD2 A:TRP374 4.8 65.1 1.0
CZ2 A:TRP374 4.9 62.6 1.0
CG A:TRP373 4.9 76.6 1.0
CD1 A:TRP373 5.0 81.4 1.0

Arsenic binding site 2 out of 3 in 4llh

Go back to Arsenic Binding Sites List in 4llh
Arsenic binding site 2 out of 3 in the Substrate Bound Outward-Open State of the Symporter Betp


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Substrate Bound Outward-Open State of the Symporter Betp within 5.0Å range:
probe atom residue distance (Å) B Occ
B:As601

b:0.1
occ:1.00
AS1 B:1Y8601 0.0 0.1 1.0
C8 B:1Y8601 1.8 0.4 1.0
C6 B:1Y8601 1.8 0.9 1.0
C7 B:1Y8601 1.8 0.3 1.0
C5 B:1Y8601 2.0 86.4 1.0
C4 B:1Y8601 3.0 96.3 1.0
O6 B:1Y8601 3.3 93.8 1.0
CD2 B:TRP373 4.0 57.9 1.0
CE2 B:TRP373 4.1 56.4 1.0
CD2 B:TRP374 4.3 56.9 1.0
CD2 B:TRP377 4.3 68.7 1.0
CE2 B:TRP374 4.3 57.9 1.0
CE3 B:TRP373 4.3 57.4 1.0
CG B:TRP373 4.3 54.5 1.0
NE1 B:TRP373 4.4 51.5 1.0
CZ2 B:TRP373 4.4 59.4 1.0
CE3 B:TRP374 4.5 63.8 1.0
CE2 B:TRP377 4.5 71.8 1.0
CZ2 B:TRP374 4.5 58.5 1.0
CE3 B:TRP377 4.5 68.7 1.0
CD1 B:TRP373 4.5 53.9 1.0
CG B:TRP377 4.6 63.7 1.0
CZ3 B:TRP374 4.6 67.6 1.0
CZ3 B:TRP373 4.6 57.8 1.0
CH2 B:TRP374 4.7 63.9 1.0
OH B:TYR197 4.7 50.5 1.0
CH2 B:TRP373 4.7 60.0 1.0
O B:TRP373 4.7 53.1 1.0
CG B:TRP374 4.7 55.3 1.0
NE1 B:TRP374 4.8 62.1 1.0
NE1 B:TRP377 4.8 68.6 1.0
O B:GLY149 4.8 68.6 1.0
CZ2 B:TRP377 4.9 75.3 1.0
CD1 B:TRP377 4.9 65.8 1.0
CZ3 B:TRP377 4.9 70.7 1.0
C B:TRP373 4.9 51.3 1.0
CA B:TRP374 5.0 47.2 1.0
CD1 B:TRP374 5.0 63.0 1.0

Arsenic binding site 3 out of 3 in 4llh

Go back to Arsenic Binding Sites List in 4llh
Arsenic binding site 3 out of 3 in the Substrate Bound Outward-Open State of the Symporter Betp


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 3 of Substrate Bound Outward-Open State of the Symporter Betp within 5.0Å range:
probe atom residue distance (Å) B Occ
C:As603

b:0.7
occ:1.00
AS1 C:1Y8603 0.0 0.7 1.0
C6 C:1Y8603 1.7 48.0 1.0
C8 C:1Y8603 1.7 71.0 1.0
C7 C:1Y8603 1.8 0.6 1.0
C5 C:1Y8603 2.0 94.1 1.0
C4 C:1Y8603 3.0 89.8 1.0
OD2 C:ASP153 3.6 87.3 1.0
OD1 C:ASP153 3.9 90.4 1.0
CG C:ASP153 4.0 87.6 1.0
O C:ALA148 4.2 68.9 1.0
O6 C:1Y8603 4.2 89.7 1.0
O C:HOH716 4.2 40.2 1.0
CG2 C:VAL381 4.8 34.2 1.0
CZ3 C:TRP377 4.9 70.4 1.0
CE3 C:TRP377 4.9 60.0 1.0

Reference:

C.Perez, B.Faust, A.R.Mehdipour, K.A.Francesconi, L.R.Forrest, C.Ziegler. Substrate-Bound Outward-Open State of the Betaine Transporter Betp Provides Insights Into Na(+) Coupling. Nat Commun V. 5 4231 2014.
ISSN: ESSN 2041-1723
PubMed: 25023443
DOI: 10.1038/NCOMMS5231
Page generated: Sun Jul 6 23:49:29 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy