Arsenic in PDB 6j0e: Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression

The structure of Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression, PDB code: 6j0e was solved by C.Prabaharan, P.Kandavelu, C.Packianathan, P.B.Rosen, S.Thiyagarajan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.79 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.770, 46.387, 121.952, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 26.4

The binding sites of Arsenic atom in the Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression (pdb code 6j0e). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression, PDB code: 6j0e:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression within 5.0Å range: probe atom residue distance (Å) B Occ A:As201 b:24.3 occ:1.00 SG A:CYS16 2.3 23.4 1.0 SG B:CYS55 2.3 23.6 1.0 SG A:CYS15 2.4 26.5 1.0 CB A:CYS16 3.1 24.3 1.0 CB B:CYS55 3.1 23.6 1.0 C B:GLY54 3.5 24.0 1.0 CB A:CYS15 3.5 24.8 1.0 N B:CYS55 3.6 20.4 1.0 C A:CYS15 3.6 29.2 1.0 O A:CYS15 3.7 31.8 1.0 O B:GLY54 3.7 26.4 1.0 N A:CYS16 3.8 30.2 1.0 O B:ALA51 3.9 31.4 1.0 CA B:CYS55 3.9 21.6 1.0 CA B:GLY54 4.0 32.9 1.0 CA A:CYS16 4.0 30.7 1.0 CA A:CYS15 4.1 24.9 1.0 CA B:ALA51 4.2 28.9 1.0 C B:ALA51 4.5 29.2 1.0 CB B:ALA51 4.5 31.2 1.0 N A:GLY115 4.6 17.5 1.0 N B:GLY54 4.6 34.2 1.0

Arsenic binding site 2 out of 2 in the Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Structures of Two Arsr As(III)-Responsive Repressors: Implications For the Mechanism of Derepression within 5.0Å range: probe atom residue distance (Å) B Occ B:As201 b:7.8 occ:1.00 SG B:CYS15 2.3 10.9 1.0 SG B:CYS16 2.3 9.4 1.0 SG A:CYS55 2.3 11.6 1.0 CB B:CYS16 3.0 10.8 1.0 CB A:CYS55 3.1 11.6 1.0 CB B:CYS15 3.2 10.8 1.0 C A:GLY54 3.4 11.7 1.0 N A:CYS55 3.4 11.6 1.0 N B:CYS16 3.5 9.8 1.0 C B:CYS15 3.7 8.4 1.0 O A:ALA51 3.8 13.5 1.0 O A:GLY54 3.8 10.1 1.0 CA A:CYS55 3.8 11.1 1.0 CA B:CYS16 3.8 11.1 1.0 CA A:GLY54 3.9 14.8 1.0 CA B:CYS15 4.1 12.5 1.0 O B:HOH345 4.2 15.8 1.0 CA A:ALA51 4.2 12.6 1.0 O B:CYS15 4.3 5.5 1.0 C A:ALA51 4.5 12.6 1.0 N A:GLY54 4.6 14.8 1.0 O A:LEU50 4.7 11.0 1.0 N B:GLY115 4.7 7.6 1.0 CB A:ALA51 4.7 12.3 1.0 N B:CYS15 5.0 11.8 1.0

C.Prabaharan, P.Kandavelu, C.Packianathan, B.P.Rosen, S.Thiyagarajan. Structures of Two Arsr As(III)-Responsive Transcriptional Repressors: Implications For the Mechanism of Derepression. J.Struct.Biol. V. 207 209 2019.
ISSN: ESSN 1095-8657
PubMed: 31136796
DOI: 10.1016/J.JSB.2019.05.009