Arsenic in PDB 6sa0: Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp

The structure of Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp, PDB code: 6sa0 was solved by N.C.Brissett, A.J.Doherty, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	58.07 / 2.21
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	136.059, 136.059, 133.479, 90.00, 90.00, 120.00
R / Rfree (%)	17.5 / 20.7

The structure of Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp also contains other interesting chemical elements:

Manganese

(Mn)

4 atoms

The binding sites of Arsenic atom in the Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp (pdb code 6sa0). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total only one binding site of Arsenic was determined in the Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp, PDB code: 6sa0:

Arsenic binding site 1 out of 1 in the Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Ternary Complex of Prim-Polc From Mycobacterium Smegmatis with 2NT Gapped Dna and Upnhpp within 5.0Å range: probe atom residue distance (Å) B Occ A:As404 b:0.5 occ:1.00 AS A:CAC404 0.0 0.5 1.0 O1 A:CAC404 1.7 0.0 1.0 O2 A:CAC404 1.9 0.9 1.0 C1 A:CAC404 2.0 0.8 1.0 C2 A:CAC404 2.0 0.7 1.0 H13 A:CAC404 2.5 0.5 1.0 H11 A:CAC404 2.5 0.5 1.0 H22 A:CAC404 2.5 0.5 1.0 H12 A:CAC404 2.5 0.5 1.0 H23 A:CAC404 2.5 0.5 1.0 H21 A:CAC404 2.5 0.5 1.0 O2 A:EDO405 3.4 79.1 1.0 HO2 A:EDO405 3.7 95.0 1.0 O A:HOH529 3.7 56.5 1.0 O A:HOH539 3.7 49.8 1.0 O A:HOH532 4.0 42.3 1.0 CE A:LYS249 4.1 63.1 1.0 O1 A:EDO405 4.2 64.9 1.0 O A:HOH613 4.2 52.3 1.0 NZ A:LYS249 4.6 75.2 1.0 C2 A:EDO405 4.7 71.7 1.0 HO1 A:EDO405 4.8 77.9 1.0 OH A:TYR74 4.8 53.0 1.0 NH2 A:ARG248 4.9 31.3 1.0

N.C.Brissett, K.Zabrady, P.Plocinski, J.Bianchi, M.Korycka-Machala, A.Brzostek, J.Dziadek, A.J.Doherty. Molecular Basis For Dna Repair Synthesis on Short Gaps By Mycobacterial Primase-Polymerase C. Nat Commun V. 11 4196 2020.
ISSN: ESSN 2041-1723
PubMed: 32826907
DOI: 10.1038/S41467-020-18012-8