Arsenic in PDB 8ttu: Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274)

The structure of Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274), PDB code: 8ttu was solved by Q.Guo, K.-E.Chen, B.M.Collins, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.25 / 2.36
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	37.544, 74.497, 102.529, 90, 90, 90
R / Rfree (%)	19.8 / 25.1

The binding sites of Arsenic atom in the Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274) (pdb code 8ttu). This binding sites where shown within 5.0 Angstroms radius around Arsenic atom.
In total 2 binding sites of Arsenic where determined in the Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274), PDB code: 8ttu:
Jump to Arsenic binding site number: 1; 2;

Arsenic binding site 1 out of 2 in the Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274)


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 1 of Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274) within 5.0Å range: probe atom residue distance (Å) B Occ A:As421 b:59.0 occ:1.00 AS A:CAF421 0.0 59.0 1.0 O1 A:CAF421 1.6 57.8 1.0 CE1 A:CAF421 2.0 56.0 1.0 CE2 A:CAF421 2.0 49.5 1.0 SG A:CAF421 2.3 48.9 1.0 CB A:CAF421 3.4 43.4 1.0 CA A:CAF421 3.5 42.7 1.0 N A:CAF421 3.8 35.4 1.0 OG1 A:THR420 3.8 39.4 1.0 C A:THR420 4.3 40.2 1.0 O A:MET417 4.5 38.0 1.0 O A:THR420 4.5 45.6 1.0 CG A:LYS398 4.6 47.9 1.0 O A:LYS394 4.7 53.1 1.0 CA A:ALA395 4.8 53.5 1.0 CB A:LYS398 4.9 46.2 1.0 C A:CAF421 4.9 51.3 1.0 CB A:THR420 4.9 37.1 1.0

Arsenic binding site 2 out of 2 in the Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274)


Mono view


Stereo pair view

A full contact list of Arsenic with other atoms in the As binding site number 2 of Structure of SNX27 Ferm Complexed with FAM21A Repeat 19 (1261 - 1274) within 5.0Å range: probe atom residue distance (Å) B Occ A:As519 b:77.7 occ:1.00 AS A:CAF519 0.0 77.7 1.0 O1 A:CAF519 1.6 95.5 1.0 CE2 A:CAF519 2.0 197.9 1.0 CE1 A:CAF519 2.0 158.2 1.0 SG A:CAF519 2.2 77.8 1.0 CB A:CAF519 3.3 51.6 1.0 NH1 A:ARG516 4.0 55.6 1.0 C A:CAF519 4.0 59.9 1.0 O A:CAF519 4.2 53.9 1.0 N A:GLU520 4.2 61.5 1.0 CA A:CAF519 4.3 51.5 1.0 CG A:GLU520 4.3 48.8 1.0 CZ A:ARG516 4.4 50.1 1.0 CD A:ARG516 4.4 38.2 1.0 NE A:ARG516 4.5 44.4 1.0 CA A:GLU520 4.5 50.8 1.0 CD1 A:TRP523 4.6 70.9 1.0 O A:ARG516 4.8 41.8 1.0

Q.Guo, K.E.Chen, M.Gimenez-Andres, A.P.Jellett, Y.Gao, B.Simonetti, M.Liu, C.M.Danson, K.J.Heesom, P.J.Cullen, B.M.Collins. Structural Basis For Coupling of the Wash Subunit FAM21 with the Endosomal SNX27-Retromer Complex. Proc.Natl.Acad.Sci.Usa V. 121 41121 2024.
ISSN: ESSN 1091-6490
PubMed: 39116126
DOI: 10.1073/PNAS.2405041121